Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

Tumor hypoxia is a common feature of the microenvironment in solid tumors, primarily due to
an inadequate, and heterogeneous vascular network. It is associated with resistance to …

Chemoradiotherapy (CRT) refers to the combined administration of both chemotherapy and
radiotherapy as an anticancer treatment. Over the years, CRT has become an established …

As we mark 150 years since the birth of Marie Curie, we reflect on the global advances
made in radiation oncology and the current status of radiation therapy (RT) research. Large …

Radiation-induced chromosomal aberrations represent an early marker of late effects,
including cell killing and transformation. The measurement of cytogenetic damage in tissues …

DNA damage-inducing therapies are of tremendous value for cancer treatment and function
by the direct or indirect formation of DNA lesions and subsequent inhibition of cellular …

With the increasing prevalence of Parkinson's disease (PD), there is an immediate need to
interdict disease signs and symptoms. In recent years this need was met through therapeutic …

Cancer immunotherapy, including immune checkpoint blockade and adoptive CAR T‐cell
therapy, has clearly established itself as an important modality to treat melanoma and other …

Over the past 25 years, there has been an unparalleled increase in understanding of cancer
biology. This transformation is exemplified by Hanahan and Weinberg's decision in 2011 to …