Rare ginsenosides are the deglycosylated secondary metabolic derivatives of major
ginsenosides, and they are more readily absorbed into the bloodstream and function as …

We critically assess the proposal that succinate-fuelled reverse electron flow (REF) drives
mitochondrial matrix superoxide production from Complex I early in reperfusion, thus acting …

Myelin degeneration and white matter loss resulting from oligodendrocyte (OL) death are
early events in Alzheimer's disease (AD) that lead to cognitive deficits; however, the …

As human pluripotent stem cells (hPSCs) exit pluripotency, they are thought to switch from a
glycolytic mode of energy generation to one more dependent on oxidative phosphorylation …

In this study, earthworm (Eisenia fetida) brain was chosen as targeted receptors to probe the
mechanisms of oxidative stress-related neurotoxicity, genotoxicity, and behavioral …

New treatments are needed to protect the myocardium against the detrimental effects of
acute ischaemia/reperfusion (IR) injury following an acute myocardial infarction (AMI), in …

Mitochondrial dysfunction is the main cause of damage to the pathological mechanism of
ischemic cardiomyopathy. In addition, mitochondrial dysfunction can also affect the …

Metabolic alterations, a hallmark of cancer, enable tumor cells to adapt to their environment
by modulating glucose, lipid, and amino acid metabolism, which fuels rapid growth and …

The major challenge in oral cancer is the lack of state‐of‐the‐art treatment modality that
effectively cures cancer while preserving oral functions. Recent insights into tumor metabolic …

Cerebral ischemia induces neuronal cell death in different ways and mitochondrial
dysfunction is an important cause. Astragaloside IV (AIV) is a natural saponin abandent in …