We identified an aldoxime dehydratase (Oxd) gene in the 5′-flanking region of the nitrile
hydratase–amidase gene cluster in the photoreactive iron-type nitrile hydratase-producer …

Nitrile and amide bioconversions have received attention through their ability to provide a
range of commercially important chemicals. These bioconversions are mediated by distinct …

Because enzyme-catalyzed reactions exhibit higher enantioselectivity, regioselectivity,
substrate specificity, and stability, they require mild conditions to react while prompting …

Recent advances in enantioselective biotransformations of nitriles utilizing nitrile-
hydrolyzing microorganisms and enzymes are summarized in this article. Various examples …

Active sites may be regarded as layers of residues, whereby the residues that interact
directly with substrate also interact with residues in a second shell and these in turn interact …

Two pathways of enzymatic hydrolysis of nitriles to carboxylic acids are known today. Under
the action of nitrilases, nitriles turn into carboxylic acids in a single step via the addition of …

The gene cluster containing the nitrile hydratase (NHase) and amidase genes of a moderate
thermophile, B. pallidus RAPc8 has been cloned and sequenced. The (5.9 kb) section of …

Thermal stability is of great importance for industrial enzymes. Here we explored the thermal-
stable mechanism of thermophilic nitrile hydratases (NHases) utilizing a molecular dynamic …

A gene cluster responsible for aldoxime metabolism in the glutaronitrile degrader
Pseudomonas sp. K-9 was analyzed genetically and enzymatically. The cluster was …

Rhodococcus strains are important biocatalysts used for biotechnological production of
acrylamide catalysed by a nitrile hydratase (NHase) containing cobalt. This metalloenzyme …