CRISPR/Cas-powered nanobiosensors for diagnostics

QA Phan, LB Truong, D Medina-Cruz, C Dincer… - Biosensors and …, 2022 - Elsevier
CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …

The spread of antibiotic resistance genes in vivo model

S Tao, H Chen, N Li, T Wang… - Canadian Journal of …, 2022 - Wiley Online Library
Infections caused by antibiotic‐resistant bacteria are a major public health threat. The
emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical …

Nutrition influences immunity: Diet and host-parasite interactions

I Eleftherianos, W Zhang, G Tettamanti, L Daley… - Insect Biochemistry and …, 2024 - Elsevier
Nutrition plays a major role in host immune responses and in pathogen resistance.
Understanding the network that modulates the relationship between nutrition and immunity …

Genome analysis of a halophilic Virgibacillus halodenitrificans ASH15 revealed salt adaptation, plant growth promotion, and isoprenoid biosynthetic machinery

A Sharma, RN Singh, XP Song, RK Singh… - Frontiers in …, 2023 - frontiersin.org
Globally, due to widespread dispersion, intraspecific diversity, and crucial ecological
components of halophilic ecosystems, halophilic bacteria is considered one of the key …

Applications of CRISPR-Cas9 in Alzheimer's disease and related disorders

LM De Plano, G Calabrese, S Conoci… - International journal of …, 2022 - mdpi.com
Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's
disease represent some of the most prevalent neurodegenerative disorders afflicting …

CRISPR/Cas-based biosensor as a new age detection method for pathogenic bacteria

J Chakraborty, AA Chaudhary, SUD Khan… - ACS …, 2022 - ACS Publications
Methods enabling rapid and on-site detection of pathogenic bacteria are a prerequisite for
public health assurance, medical diagnostics, ensuring food safety and security, and …

CRISPR/Cas9: regulations and challenges for law enforcement to combat its dual-use

AK Wani, N Akhtar, S Shukla - Forensic science international, 2022 - Elsevier
For many years, scientists have aspired to edit any DNA segment of living organisms
precisely, and with the discovery of CRISPR/Cas9, they have moved closer to achieving …

Fitness costs of CRISPR-Cas systems in bacteria

M Zaayman, RM Wheatley - Microbiology, 2022 - microbiologyresearch.org
CRISPR-Cas systems provide bacteria with both specificity and adaptability in defence
against invading genetic elements. From a theoretical perspective, CRISPR-Cas systems …

Nanopores Reveal the Stoichiometry of Single Oligoadenylates Produced by Type III CRISPR-Cas

DF Navas, JA Steens, C de Lannoy, B Noordijk… - ACS …, 2024 - pmc.ncbi.nlm.nih.gov
Cyclic oligoadenylates (cOAs) are small second messenger molecules produced by the type
III CRISPR-Cas system as part of the prokaryotic immune response. The role of cOAs is to …

Nanopores Reveal the Stoichiometry of Single Oligoadenylates Produced by Type III CRISPR-Cas

D Fuentenebro Navas, JA Steens, C de Lannoy… - ACS Nano, 2024 - ACS Publications
Cyclic oligoadenylates (cOAs) are small second messenger molecules produced by the type
III CRISPR-Cas system as part of the prokaryotic immune response. The role of cOAs is to …