ELANE mutations in cyclic and severe congenital neutropenia: genetics and pathophysiology

MS Horwitz, SJ Corey, HL Grimes… - Hematology/Oncology …, 2013 - hemonc.theclinics.com
Normal neutrophil counts in peripheral blood typically range between 1500 to 8500 cells/mL
after the age of 1 year, 1 although they vary among individuals from different parts of the …

Population-based differences in treatment outcome following anticancer drug therapies

BBY Ma, EP Hui, TSK Mok - The lancet oncology, 2010 - thelancet.com
Population-based differences in toxicity and clinical outcome following treatment with
anticancer drugs have an important effect on oncology practice and drug development …

[HTML][HTML] Global inequities in precision medicine and molecular cancer research

TM Drake, SR Knight, EM Harrison, K Søreide - Frontiers in Oncology, 2018 - frontiersin.org
Precision medicine based upon molecular testing is heralded as a revolution in how cancer
is prevented, diagnosed, and treated. Large efforts across the world aim to conduct …

[HTML][HTML] The contribution of race to breast tumor microenvironment composition and disease progression

G Kim, JM Pastoriza, JS Condeelis, JA Sparano… - Frontiers in …, 2020 - frontiersin.org
Breast cancer is the second most commonly diagnosed cancer in American women
following skin cancer. Despite overall decrease in breast cancer mortality due to advances …

Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos

D Jain, CJ Hodonsky, UM Schick… - Human molecular …, 2017 - academic.oup.com
Circulating white blood cell (WBC) counts (neutrophils, monocytes, lymphocytes,
eosinophils, basophils) differ by ethnicity. The genetic factors underlying basal WBC traits in …

The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry

H Kulkarni, VC Marconi, W He… - Blood, The Journal …, 2009 - ashpublications.org
Persons of African ancestry, on average, have lower white blood cell (WBC) counts than
those of European descent (ethnic leukopenia), but whether this impacts negatively on HIV …

Biological responses to COVID-19: Insights from physiological and blood biomarker profiles

R Zakeri, A Pickles, E Carr, DM Bean… - Current research in …, 2021 - Elsevier
Background Understanding the spectrum and course of biological responses to coronavirus
disease 2019 (COVID-19) may have important therapeutic implications. We sought to …

[HTML][HTML] Hematological indices in the adult Saudi population: Reference intervals by gender, age, and region

NA Shaheen, H Rehan, A Moghairi, G Gmati… - Frontiers in …, 2022 - frontiersin.org
Introduction Hematological parameters are critical in disease diagnosis, management, and
monitoring; however, complete blood count (CBC) reference intervals vary across …

[HTML][HTML] Breast cancer in the Caribbean

K Samaroo, A Hosein, LK Olivier, J Ali - Cureus, 2021 - ncbi.nlm.nih.gov
Breast cancer (BC) is one of the leading causes of death among women globally. In the
Caribbean, there is a higher mortality rate compared with North American and European …

How to differentiate congenital from noncongenital chronic neutropenia at the first medical examination? Proposal of score: A pilot study from the French Severe …

N Bejjani, B Beaupain, Y Bertrand… - Pediatric Blood & …, 2017 - Wiley Online Library
Objectives We developed a diagnostic score to differentiate congenital from noncongenital
neutropenia at the time of diagnosis using reliable data collected at the first visit of a patients …