Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values

K Dhama, SK Latheef, M Dadar, HA Samad… - Frontiers in molecular …, 2019 - frontiersin.org
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

GPCR-Hippo signaling in cancer

J Luo, FX Yu - Cells, 2019 - mdpi.com
The Hippo signaling pathway is involved in tissue size regulation and tumorigenesis.
Genetic deletion or aberrant expression of some Hippo pathway genes lead to enhanced …

Angiogenin promotes colorectal cancer metastasis via tiRNA production

S Li, X Shi, M Chen, N Xu, D Sun, R Bai… - … Journal of Cancer, 2019 - Wiley Online Library
Metastasis of colorectal cancer (CRC) is the leading cause of CRC‐associated mortality.
Angiogenin (ANG), a member of the ribonuclease A superfamily, not only activates …

tRNA-derived small RNAs and their potential roles in cardiac hypertrophy

J Cao, DB Cowan, DZ Wang - Frontiers in Pharmacology, 2020 - frontiersin.org
Transfer RNAs (tRNAs) are abundantly expressed, small non-coding RNAs that have long
been recognized as essential components of the protein translation machinery. The tRNA …

Angiogenesis, lymphangiogenesis, and inflammation in chronic obstructive pulmonary disease (COPD): few certainties and many outstanding questions

R Poto, S Loffredo, F Palestra, G Marone, V Patella… - Cells, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation,
predominantly affecting the lung parenchyma and peripheral airways, that results in …

tRNA-derived small RNAs: novel insights into the pathogenesis and treatment of cardiovascular diseases

S Wang, Z Luo, L Yuan, X Lin, Y Tang, L Yin… - Journal of …, 2023 - Springer
Abstract tRNA-derived small RNAs (tsRNAs) are non-coding RNAs with diverse functions in
various diseases. Although research on tsRNAs has focused on their roles in cancer, such …

Melatonin protects the heart and endothelium against high fructose corn syrup consumption–induced cardiovascular toxicity via SIRT-1 signaling

M Savran, H Asci, O Ozmen… - Human & …, 2019 - journals.sagepub.com
High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via
oxidative stress and inflammation. The aim of this study is to demonstrate the protective …

Emerging roles of novel small non-coding regulatory RNAs in immunity and cancer

D Rosace, J López, S Blanco - RNA biology, 2020 - Taylor & Francis
The term small non-coding RNAs (ncRNAs) refers to all those RNAs that even without
encoding for a protein, can play important functional roles. Transfer RNA and ribosomal …

Plasma proteomics of diabetic kidney disease among Asians with younger-onset type 2 diabetes

RL Gurung, H Zheng, HWL Koh, JJ Liu… - The Journal of …, 2024 - academic.oup.com
Context Patients with younger onset of type 2 diabetes (YT2D) have increased risk for
kidney failure compared to those with late onset. However, the mechanism of diabetic kidney …

Human and mouse angiogenins: Emerging insights and potential opportunities

MF Sultana, H Abo, H Kawashima - Frontiers in microbiology, 2022 - frontiersin.org
Angiogenin, a well-known angiogenic factor, is crucial to the angiogenesis in
gastrointestinal tumors. Human angiogenin has only one gene, whereas the murine …