Substituted 2-arylbenzothiazoles have emerged in recent years as an important
pharmacophore in a number of diagnostic and therapeutic settings. Attractive features of …

Cancer and oxidative stress are interrelated, with reactive oxygen species (ROS) playing
crucial roles in physiological processes and oncogenesis. Excessive ROS levels can induce …

We present a new efficient green synthetic protocol for introduction of substituents to the C-6
position of 2-arylbenzothiazole nuclei. Newly synthesized compounds were designed to …

Parasitic infections constitute one of the most widespread human health problems, and most
of them occur through contaminated food or water. The human intestine is a major target of …

The synthesis, FT-IR, 1H and 13C NMR characterisation, as well as crystal and molecular
structure determined by single-crystal X-ray diffraction data, of two azo dyes derived from 6 …

Recently, heterocyclic compounds analogues and their derivatives have attracted strong
interest in medicinal chemistry due to their biological and pharmacological properties. The …

A series of new diamidino-, diisopropylamidino-, and diimidazolinyl-substituted derivatives
of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes were successfully …

Novel amidino-derivatives of phenylene-bisbenzothiazoles were synthesized and tested for
their antiproliferative activity against several human cancer cell lines, as well as DNA …

The efficient synthesis of new bis-substituted nitro-amidino, amino-amidino (10a, 10b–13a,
13b) and previously prepared diamidino 2-phenyl-benzothiazoles (9a, 9b) is described. The …

Novel diamidino substituted conformationally restricted derivatives of bis-benzothiazolyl-
pyridines and pyrazine were synthesized and their antiproliferative activity against several …