A review on quantitative multiplexed proteomics

N Pappireddi, L Martin, M Wühr - Chembiochem, 2019 - Wiley Online Library
Over the last few decades, mass spectrometry‐based proteomics has become an
increasingly powerful tool that is now able to routinely detect and quantify thousands of …

Protein analysis by shotgun/bottom-up proteomics

Y Zhang, BR Fonslow, B Shan, MC Baek… - Chemical …, 2013 - ACS Publications
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Potential-resolved multicolor electrochemiluminescence for multiplex immunoassay in a single sample

W Guo, H Ding, C Gu, Y Liu, X Jiang… - Journal of the …, 2018 - ACS Publications
Electrochemiluminescence (ECL) is a highly successful technique used in commercial
immunoassays for clinical diagnosis. Developing an ECL-based multiplex immunoassay …

Parallel reaction monitoring for high resolution and high mass accuracy quantitative, targeted proteomics

AC Peterson, JD Russell, DJ Bailey… - Molecular & cellular …, 2012 - ASBMB
Selected reaction monitoring on a triple quadrupole mass spectrometer is currently
experiencing a renaissance within the proteomics community for its, as yet, unparalleled …

Data analysis strategies for targeted and untargeted LC-MS metabolomic studies: Overview and workflow

E Gorrochategui, J Jaumot, S Lacorte… - TrAC Trends in Analytical …, 2016 - Elsevier
Data analysis is a very challenging task in LC-MS metabolomic studies. The use of powerful
analytical techniques (eg, high-resolution mass spectrometry) provides high-dimensional …

Parallel reaction monitoring: a targeted experiment performed using high resolution and high mass accuracy mass spectrometry

N Rauniyar - International journal of molecular sciences, 2015 - mdpi.com
The parallel reaction monitoring (PRM) assay has emerged as an alternative method of
targeted quantification. The PRM assay is performed in a high resolution and high mass …

LC-MS-based metabolomics

B Zhou, JF Xiao, L Tuli, HW Ressom - Molecular BioSystems, 2012 - pubs.rsc.org
Metabolomics aims at identification and quantitation of small molecules involved in
metabolic reactions. LC-MS has enjoyed a growing popularity as the platform for …

The human serum metabolome

N Psychogios, DD Hau, J Peng, AC Guo, R Mandal… - PloS one, 2011 - journals.plos.org
Continuing improvements in analytical technology along with an increased interest in
performing comprehensive, quantitative metabolic profiling, is leading to increased interest …

Chemometric methods in data processing of mass spectrometry-based metabolomics: A review

L Yi, N Dong, Y Yun, B Deng, D Ren, S Liu… - Analytica chimica acta, 2016 - Elsevier
This review focuses on recent and potential advances in chemometric methods in relation to
data processing in metabolomics, especially for data generated from mass spectrometric …

Mass spectrometry‐based metabolomics

K Dettmer, PA Aronov… - Mass spectrometry …, 2007 - Wiley Online Library
This review presents an overview of the dynamically developing field of mass spectrometry‐
based metabolomics. Metabolomics aims at the comprehensive and quantitative analysis of …