A growing link between circadian rhythms, type 2 diabetes mellitus and Alzheimer's disease

X Peng, R Fan, L Xie, X Shi, K Dong, S Zhang… - International journal of …, 2022 - mdpi.com
Type 2 diabetes mellitus (T2DM) patients are at a higher risk of developing Alzheimer's
disease (AD). Mounting evidence suggests the emerging important role of circadian rhythms …

Effects of exercise timing on metabolic health

JI Martínez‐Montoro, J Benítez‐Porres… - Obesity …, 2023 - Wiley Online Library
The increasing prevalence of metabolic syndrome is associated with major health and
socioeconomic consequences. Currently, physical exercise, together with dietary …

Importance of Bmal1 in Alzheimer's disease and associated aging‐related diseases: mechanisms and interventions

R Fan, X Peng, L Xie, K Dong, D Ma, W Xu, X Shi… - Aging cell, 2022 - Wiley Online Library
With the aging world population, the prevalence of aging‐related disorders is on the rise.
Diseases such as Alzheimer's, type 2 diabetes mellitus (T2DM), Parkinson's …

Time for exercise? Exercise and its influence on the skeletal muscle clock

RA Martin, KA Esser - Journal of biological rhythms, 2022 - journals.sagepub.com
Circadian rhythms drive our daily behaviors to coincide with the earth's rotation on an
approximate 24-h cycle. The circadian clock mechanism present in nearly every cell is …

Exercise training modifies skeletal muscle clock gene expression but not 24‐hour rhythmicity in substrate metabolism of men with insulin resistance

JF Harmsen, M Kotte, I Habets… - The Journal of …, 2024 - Wiley Online Library
Twenty‐four hour rhythmicity in whole‐body substrate metabolism, skeletal muscle clock
gene expression and mitochondrial respiration is compromised upon insulin resistance …

Circadian clocks, redox homeostasis, and exercise: time to connect the dots?

C McClean, GW Davison - Antioxidants, 2022 - mdpi.com
Compelling research has documented how the circadian system is essential for the
maintenance of several key biological processes including homeostasis, cardiovascular …

Effects of diet and exercise on circadian rhythm: role of gut microbiota in immune and metabolic systems

Y Cai, Y Liu, Z Wu, J Wang, X Zhang - Nutrients, 2023 - mdpi.com
A close relationship exists between the intestinal microbiota and the circadian rhythm, which
is mainly regulated by the central-biological-clock system and the peripheral-biological …

Exercise as a peripheral circadian clock resynchronizer in vascular and skeletal muscle aging

BSA Silva, JS Uzeloto, FS Lira, T Pereira… - International journal of …, 2021 - mdpi.com
Aging is characterized by several progressive physiological changes, including changes in
the circadian rhythm. Circadian rhythms influence behavior, physiology, and metabolic …

Ketogenic propensity is differentially related to lipid‐induced hepatic and peripheral insulin resistance

JT Mey, B Vandagmansar, WS Dantas… - Acta …, 2023 - Wiley Online Library
Aim Determine the ketogenic response (β‐hydroxybutyrate, a surrogate of hepatic
ketogenesis) to a controlled lipid overload in humans. Methods In total, nineteen young …

Circadian Rhythms, Chrononutrition, Physical Training, and Redox Homeostasis—Molecular Mechanisms in Human Health

CM Drăgoi, AC Nicolae, A Ungurianu, DM Margină… - Cells, 2024 - mdpi.com
A multitude of physiological processes, human behavioral patterns, and social interactions
are intricately governed by the complex interplay between external circumstances and …