Psoriasis and cardiovascular comorbidities: focusing on severe vascular events, cardiovascular risk factors and implications for treatment

SCS Hu, CCE Lan - International journal of molecular sciences, 2017 - mdpi.com
Psoriasis is a common and chronic inflammatory disease of the skin. It may impair the
physical and psychosocial function of patients and lead to decreased quality of life …

Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities

C Ryan, B Kirby - Dermatologic clinics, 2015 - derm.theclinics.com
Once considered to be solely a cutaneous disease, there is now robust evidence that
psoriasis is associated with systemic inflammation and a significantly increased risk of …

Shared genetic risk factors and causal association between psoriasis and coronary artery disease

MT Patrick, Q Li, R Wasikowski, N Mehta… - Nature …, 2022 - nature.com
Psoriasis and coronary artery disease (CAD) are related comorbidities that are well
established, but whether a genetic basis underlies this is not well studied. We apply trans …

[HTML][HTML] Emerging roles of adipose tissue in the pathogenesis of psoriasis and atopic dermatitis in obesity

Z Guo, Y Yang, Y Liao, Y Shi, L Zhang - JID Innovations, 2022 - Elsevier
Obesity is a growing epidemic worldwide, and it is also considered a major environmental
factor contributing to the pathogenesis of inflammatory skin diseases, including psoriasis …

Serum leptin, resistin, and adiponectin concentrations in psoriasis: a meta-analysis of observational studies

A Kyriakou, A Patsatsi, D Sotiriadis, DG Goulis - Dermatology, 2018 - karger.com
Background: Psoriasis is an immune-mediated, inflammatory disease. Adipokines contribute
to the regulation of immune-mediated processes and inflammation. Objective: The aim of our …

Adipokines in the Skin and in Dermatological Diseases

D Kovács, F Fazekas, A Oláh, D Törőcsik - International Journal of …, 2020 - mdpi.com
Adipokines are the primary mediators of adipose tissue-induced and regulated systemic
inflammatory diseases; however, recent findings revealed that serum levels of various …

Very low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: an update for dermatologists and nutritionists

L Barrea, M Megna, S Cacciapuoti… - Critical reviews in …, 2021 - Taylor & Francis
Psoriasis is a chronic skin immune-mediated disease with systemic pro-inflammatory
activation; both genetic and lifestyles factors contribute to its pathogenesis and severity. In …

Proinflammatory and anti-inflammatory cytokine profiles in psoriasis: use as laboratory biomarkers and disease predictors

C Cataldi, NL Mari, MAB Lozovoy, LMM Martins… - Inflammation …, 2019 - Springer
Objective The objectives of this study were to delineate the pro and anti-inflammatory
cytokine profiles of psoriasis and cytokine profile models that externally validate the …

Comparison of coronary artery calcium scores between patients with psoriasis and type 2 diabetes

B Mansouri, D Kivelevitch, B Natarajan… - JAMA …, 2016 - jamanetwork.com
Importance Psoriasis is associated with an increased risk of cardiovascular diseases.
Subclinical atherosclerosis in patients with psoriasis has not been compared with other …

Body mass index, abdominal fatness, weight gain and the risk of psoriasis: a systematic review and dose–response meta-analysis of prospective studies

D Aune, I Snekvik, S Schlesinger, T Norat… - European journal of …, 2018 - Springer
Greater body mass index (BMI) has been associated with increased risk of psoriasis in case–
control and cross-sectional studies, however, the evidence from prospective studies has …