Acute and long-term consequences of COVID-19 on arterial stiffness—a narrative review

IM Zota, C Stătescu, RA Sascău, M Roca, L Anghel… - Life, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
ongoing global coronavirus (COVID-19) pandemic. Although initially viewed as an acute …

Lipid compartments and lipid metabolism as therapeutic targets against coronavirus

D Cesar-Silva, FS Pereira-Dutra, ALM Giannini… - Frontiers in …, 2023 - frontiersin.org
Lipids perform a series of cellular functions, establishing cell and organelles' boundaries,
organizing signaling platforms, and creating compartments where specific reactions occur …

Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …

Statin use in COVID-19 hospitalized patients and outcomes: a retrospective study

H Kouhpeikar, H Khosaravizade Tabasi… - Frontiers in …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) might affect everyone, but people with
comorbidities such as hypertension and cardiovascular disease (CVD) may often have more …

Association of statins for primary prevention of cardiovascular diseases with hospitalization for COVID‐19: A nationwide matched population‐based cohort study

K Bouillon, B Baricault, L Semenzato… - Journal of the …, 2022 - Am Heart Assoc
Background There is little evidence on the relationship between statin use and the risk of
hospitalization attributable to COVID‐19. Methods and Results The French National …

Survival of the hospitalized patients with COVID‐19 receiving atorvastatin: A randomized clinical trial

M Ghafoori, H Saadati, M Taghavi… - Journal of medical …, 2022 - Wiley Online Library
As statins decrease the progression of sepsis and its related mortality, this study aimed to
evaluate the effect of atorvastatin on survival and symptom improvement in hospitalized …

Lipid raft integrity and cellular cholesterol homeostasis are critical for SARS-CoV-2 entry into cells

A Bakillah, FA Hejji, A Almasaud, HA Jami, A Hawwari… - Nutrients, 2022 - mdpi.com
Lipid rafts in cell plasma membranes play a critical role in the life cycle of many viruses.
However, the involvement of membrane cholesterol-rich lipid rafts in the entry of severe …

Systematic review and meta-analysis of statin use and mortality, intensive care unit admission and requirement for mechanical ventilation in COVID-19 patients

US Lao, CF Law, DT Baptista-Hon… - Journal of Clinical …, 2022 - mdpi.com
There is mounting evidence that statin use is beneficial for COVID-19 outcomes. We
performed a systematic review and meta-analysis to evaluate the association between statin …

Colchicine and high-intensity rosuvastatin in the treatment of non-critically ill patients hospitalised with COVID-19: a randomised clinical trial

T Shah, M McCarthy, I Nasir, H Archer, E Ragheb… - BMJ open, 2023 - bmjopen.bmj.com
Objective To evaluate the effect of colchicine and high-intensity rosuvastatin in addition to
standard of care on the progression of COVID-19 disease in hospitalised patients. Design A …

Statin use in relation to COVID-19 and other respiratory infections: Muscle and other considerations

BA Golomb, JH Han, PH Langsjoen… - Journal of Clinical …, 2023 - mdpi.com
Statins have been widely advocated for use in COVID-19 based on large favorable
observational associations buttressed by theoretical expected benefits. However, past …