Detection, risk factors, and functional consequences of cerebral microinfarcts
Cerebral microinfarcts are small lesions that are presumed to be ischaemic. Despite the
small size of these lesions, affected individuals can have hundreds to thousands of cerebral …
small size of these lesions, affected individuals can have hundreds to thousands of cerebral …
Ischemic brain injury in cerebral amyloid angiopathy
YD Reijmer, SJ Van Veluw… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral amyloid angiopathy (CAA) is a common form of cerebral small vessel disease and
an important risk factor for intracerebral hemorrhage and cognitive impairment. While the …
an important risk factor for intracerebral hemorrhage and cognitive impairment. While the …
Serum neurofilament light: a biomarker of neuroaxonal injury after ischemic stroke
Objective To explore the utility of serum neurofilament light chain (NfL) as a biomarker for
primary and secondary neuroaxonal injury after ischemic stroke (IS) and study its value for …
primary and secondary neuroaxonal injury after ischemic stroke (IS) and study its value for …
Serum neurofilament light is sensitive to active cerebral small vessel disease
T Gattringer, D Pinter, C Enzinger, T Seifert-Held… - Neurology, 2017 - AAN Enterprises
Objective: To explore whether serum neurofilament light chain protein (NfL) levels are
increased in patients with MRI-confirmed recent small subcortical infarcts (RSSI) compared …
increased in patients with MRI-confirmed recent small subcortical infarcts (RSSI) compared …
New treatment approaches to modify the course of cerebral small vessel diseases
Smith and Markus Cerebral Small Vessel Disease Trials 39 dysmetabolism, and glucose
dysregulation that are the primary targets for current ischemic stroke prevention. As an …
dysregulation that are the primary targets for current ischemic stroke prevention. As an …
Development of white matter hyperintensity is preceded by reduced cerebrovascular reactivity
Objective White matter hyperintensities (WMH) observed on neuroimaging of elderly
individuals are associated with cognitive decline and disability. However, the pathogenesis …
individuals are associated with cognitive decline and disability. However, the pathogenesis …
[HTML][HTML] Prevention and management of cerebral small vessel disease
V Mok, JS Kim - Journal of stroke, 2015 - ncbi.nlm.nih.gov
Lacunar infarcts/lacunes, white matter hyperintensities (WMH), and cerebral microbleeds
(CMBs) are considered various manifestations of cerebral small vessel disease (SVD) …
(CMBs) are considered various manifestations of cerebral small vessel disease (SVD) …
Long-term blood–brain barrier permeability changes in Binswanger disease
BN Huisa, A Caprihan, J Thompson, J Prestopnik… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—The blood–brain barrier (BBB) is disrupted in small vessel
disease patients with lacunes and white matter hyperintensities (WMHs). The relationship of …
disease patients with lacunes and white matter hyperintensities (WMHs). The relationship of …
Validation of a regression technique for segmentation of white matter hyperintensities in Alzheimer's disease
M Dadar, TA Pascoal, S Manitsirikul… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Segmentation and volumetric quantification of white matter hyperintensities (WMHs) is
essential in assessment and monitoring of the vascular burden in aging and Alzheimer's …
essential in assessment and monitoring of the vascular burden in aging and Alzheimer's …
Neurovascular unit dysregulation, white matter disease, and executive dysfunction: the shared triad of vascular cognitive impairment and Alzheimer disease
Executive dysfunction is the most important predictor for loss of independence in dementia.
As executive function involves the coordination of distributed cerebral functions, executive …
As executive function involves the coordination of distributed cerebral functions, executive …