Applications of fMRI in translational medicine and clinical practice

PM Matthews, GD Honey, ET Bullmore - Nature Reviews Neuroscience, 2006 - nature.com
Functional MRI (fMRI) has had a major impact in cognitive neuroscience. fMRI now has a
small but growing role in clinical neuroimaging, with initial applications to neurosurgical …

Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

High-resolution fMRI reveals laminar differences in neurovascular coupling between positive and negative BOLD responses

J Goense, H Merkle, NK Logothetis - Neuron, 2012 - cell.com
The six cortical layers have distinct anatomical and physiological properties, like different
energy use and different feedforward and feedback connectivity. It is not known if and how …

A review of calibrated blood oxygenation level‐dependent (BOLD) methods for the measurement of task‐induced changes in brain oxygen metabolism

NP Blockley, VEM Griffeth, AB Simon… - NMR in …, 2013 - Wiley Online Library
The dynamics of the blood oxygenation level‐dependent (BOLD) response are dependent
on changes in cerebral blood flow, cerebral blood volume and the cerebral metabolic rate of …

fMRI at high spatial resolution: implications for BOLD-models

J Goense, Y Bohraus, NK Logothetis - Frontiers in computational …, 2016 - frontiersin.org
As high-resolution functional magnetic resonance imaging (fMRI) and fMRI of cortical layers
become more widely used, the question how well high-resolution fMRI signals reflect the …

Theoretical and experimental investigation of the VASO contrast mechanism

MJ Donahue, H Lu, CK Jones… - … in Medicine: An …, 2006 - Wiley Online Library
Vascular space occupancy (VASO)‐dependent functional MRI (fMRI) is a blood‐nulling
technique capable of generating microvascular cerebral blood volume (CBV)‐weighted …

Characterizing resting-state brain function using arterial spin labeling

JJ Chen, K Jann, DJJ Wang - Brain connectivity, 2015 - liebertpub.com
Arterial spin labeling (ASL) is an increasingly established magnetic resonance imaging
(MRI) technique that is finding broader applications in studying the healthy and diseased …

Novel approach to the measurement of absolute cerebral blood volume using vascular‐space‐occupancy magnetic resonance imaging

H Lu, M Law, G Johnson, Y Ge… - Magnetic resonance …, 2005 - Wiley Online Library
Quantitative determination of cerebral blood volume (CBV) is important for understanding
brain physiology and pathophysiology. In this work, a novel approach is presented for …

Investigation of the neurovascular coupling in positive and negative BOLD responses in human brain at 7 T

L Huber, J Goense, AJ Kennerley, D Ivanov… - Neuroimage, 2014 - Elsevier
Decreases in stimulus-dependent blood oxygenation level dependent (BOLD) signal and
their underlying neurovascular origins have recently gained considerable interest. In this …

Origins of the BOLD post-stimulus undershoot

JJ Chen, GB Pike - Neuroimage, 2009 - Elsevier
The interpretation of the blood-oxygenation level-dependent (BOLD) post-stimulus
undershoot has been a topic of considerable interest, as the mechanisms behind this …