Crossing the blood-brain barrier: advances in nanoparticle technology for drug delivery in neuro-oncology

AM Hersh, S Alomari, BM Tyler - International journal of molecular …, 2022 - mdpi.com
The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Nanoparticles incorporated in nanofibers using electrospinning: A novel nano-in-nano delivery system

K Shetty, A Bhandari, KS Yadav - Journal of controlled release, 2022 - Elsevier
Nanofibers are cutting-edge drug delivery systems that are being utilised to treat a variety of
ailments. Nanofibers are mostly woven by electrospinning techniques that are majorly used …

Chitosan nanocomposite for tissue engineering and regenerative medicine: a review

P Gupta, S Sharma, S Jabin, S Jadoun - International journal of biological …, 2024 - Elsevier
Regenerative medicine and tissue engineering have emerged as a multidisciplinary
promising field in the quest to address the limitations of traditional medical approaches. One …

Approved nanomedicine against diseases

Y Jia, Y Jiang, Y He, W Zhang, J Zou, KT Magar… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases.
Nanotechnology represents one of the most effective approaches in elevating a drug's …

Nanocarriers as potential drug delivery candidates for overcoming the blood–brain barrier: challenges and possibilities

J Ahlawat, G Guillama Barroso, S Masoudi Asil… - Acs Omega, 2020 - ACS Publications
The design of a drug that successfully overcomes the constraints imposed by the blood–
brain barrier (BBB, which acts as a gatekeeper to the entry of substances into the brain) …

Cell-based drug delivery systems and their in vivo fate

L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

Curcumin delivery and co-delivery based on nanomaterials as an effective approach for cancer therapy

M Pourmadadi, P Abbasi, MM Eshaghi… - Journal of Drug Delivery …, 2022 - Elsevier
Throughout the world, cancer is one of the main causes of mortality, threatening the public
health in many countries. As a result, cancer therapy researchers are paying increasing …

Polyester based polymeric nano and microparticles for pharmaceutical purposes: A review on formulation approaches

F Molavi, M Barzegar-Jalali, H Hamishehkar - Journal of Controlled …, 2020 - Elsevier
The novel polymeric particulate systems show high potential in their clinical effectiveness.
Nevertheless, many of the drug delivery systems developed in the research laboratories …

Drug delivery by ultrasound-responsive nanocarriers for cancer treatment

K Entzian, A Aigner - Pharmaceutics, 2021 - mdpi.com
Conventional cancer chemotherapies often exhibit insufficient therapeutic outcomes and
dose-limiting toxicity. Therefore, there is a need for novel therapeutics and formulations with …