The poly-l-proline type II (PPII) helix in recent years has emerged clearly as a structural class
not only of fibrillar proteins (in collagen, PPII is a dominant conformation) but also of the …

Modern classification of the family of human small heat shock proteins (the so-called HSPB)
is presented, and the structure and properties of three members of this family are analyzed …

Enamel is a hard nanocomposite bioceramic with significant resilience that protects the
mammalian tooth from external physical and chemical damages. The remarkable …

Biomineralization can be considered as nature's strategy to produce and sustain
biominerals, primarily via creation of hard tissues for protection and support. This review …

Mature tooth enamel is acellular and does not regenerate itself. Developing technologies
that rebuild tooth enamel and preserve tooth structure is therefore of great interest …

The complex nature of macromolecular interactions usually makes it very hard to identify the
molecular-level mechanisms that ultimately dictate the result of these interactions. This is …

Amelogenins make up a class of proteins associated with the formation of mineralized
enamel in vertebrates, possess highly conserved N-and C-terminal sequence regions, and …

Background: Enamel matrix derivative (EMD), the active component of Emdogain®, is a
viable option in the treatment of periodontal disease owing to its ability to regenerate lost …

The gradual discovery of functional domains in native enamel matrix proteins has enabled
the design of smart bioinspired peptides for tooth enamel mimetics and repair. In this study …

Amelogenin (Amel) accelerates the nucleation of hydroxyapatite (HAP) in supersaturated
solutions of calcium phosphate (Ca− P), shortening the induction time (delay period), under …