Paclitaxel (PTX) is an effective drug against diseases such as lung cancer, ovarian cancer,
and breast cancer. However, multidrug resistance limits the clinical applications of this drug …

The opposing effect of the blood–brain barrier against the delivery of most drugs warrants
the need for an efficient brain targeted drug delivery system for the successful management …

Etodolac (ETD), a nonsteroidal anti-inflammatory drug, exhibits antinflammatory, analgesic,
and antipyretic activity. The main type of ETD administration is oral route, which is …

Nanostructured lipid carriers (NLC) are a recent approach for the delivery of poorly soluble
drugs with low oral bioavailability. The oral antidiabetic Repaglinide (RPG) was loaded into …

Cancer is a multifactorial disease necessitating identification of novel targets for its
treatment. Inhibition of Bcl-2 for triggered pro-apoptotic signaling is considered a promising …

Despite the wide use of paclitaxel (PTX) as antitumor drug, its intravenous administration is
still limited by the low aqueous solubility (< 1.0 μg/mL; log P= 3.96). Taxol® is the main …

Objectives: The study aimed to prepare carbamazepine in solid lipid nanoparticle form (CBZ-
SLN) in order to enhance its anticonvulsant effect. Method: Eight formulations of CBZ-SLNs …

Resveratrol (Res), a potent nutraceutical, holds promise in ameliorating cancer and
catalyzing breakthroughs in cancer therapy. Despite numerous preclinical studies on its …

Background: The vasoselective calcium-channel blocker lercanidipine hydrochloride (LCH)
is poorly absorbed orally (only 10% bioavailability) owing to its low solubility and hepatic …

Voriconazole (VOZ) is an antifungal drug having poor aqueous solubility. VOZ
nanostructured lipid carrier (VNLC) was prepared by using melt emulsification followed by …