Sex-biased T-cell exhaustion drives differential immune responses in glioblastoma

J Lee, M Nicosia, ES Hong, DJ Silver, C Li, D Bayik… - Cancer discovery, 2023 - AACR
Sex differences in glioblastoma (GBM) incidence and outcome are well recognized, and
emerging evidence suggests that these extend to genetic/epigenetic and cellular …

α‐Ketoglutarate–Dependent KDM6 Histone Demethylases and Interferon‐Stimulated Gene Expression in Lupus

EN Montano, M Bose, L Huo… - Arthritis & …, 2024 - Wiley Online Library
Objective We aimed to investigate the hypothesis that interferon (IFN)–stimulated gene (ISG)
expression in systemic lupus erythematosus (SLE) monocytes is linked to changes in …

[HTML][HTML] Exploring genetic and immune underpinnings of the sexual dimorphism in tumor response to immune checkpoints inhibitors: A narrative review

G Mazzaschi, F Quaini, S Buti - Current Research in Pharmacology and …, 2023 - Elsevier
Introduction In spite of the undisputed relevance of sex as critical biologic variable of the
immune landscape, still limited is our understanding of the basic mechanisms implicated in …

Analysis of the impact of handling and culture on the expansion and functionality of NK cells

S Martin-Iglesias, L Herrera, S Santos… - Frontiers in …, 2023 - frontiersin.org
Natural killer (NK) cells are lymphocytes of the innate immune system that play a key role in
the elimination of tumor and virus-infected cells. Unlike T cells, NK cell activation is …

XXtra killer cells

A Reid Cahn, AM Farkas - Nature Reviews Immunology, 2022 - nature.com
XXtra killer cells | Nature Reviews Immunology Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …