Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Lipids are essential building blocks synthesized by complex molecular pathways and
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …

Congenital generalized lipodystrophy (CGL) is a heterogeneous autosomal recessive
disorder characterized by a near complete lack of adipose tissue from birth and, later in life …

Insulin resistance is among the most prevalent endocrine derangements in the world, and it
is closely associated with major diseases of global reach including diabetes mellitus …

After entering a cell, most small molecule fluorescent probes are dispersed in the cytoplasm
before they then accumulate in a specific organelle or subcellular zone. Molecules that can …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

Caveolae, flask-like invaginations of the plasma membrane, were discovered nearly 60
years ago. Originally regarded as fixation artifacts of electron microscopy, the functional role …

Caveolae are 70–100 nm diameter plasma membrane invaginations found in abundance in
adipocytes, endothelial cells, myocytes, and fibroblasts. Their bulb-shaped membrane …

Over the past decade, interest in caveolae biology has peaked. These small bulb-shaped
plasma membrane invaginations of 50–80 nm diameter present in most cell types have …

The lipid droplet (LD), an organelle that exists ubiquitously in various organisms, from
bacteria to mammals, has attracted much attention from both medical and cell biology fields …