The role of nicotinamide in cancer chemoprevention and therapy

IP Nikas, SA Paschou, HS Ryu - Biomolecules, 2020 - mdpi.com
Nicotinamide (NAM) is a water-soluble form of Vitamin B3 (niacin) and a precursor of
nicotinamide-adenine dinucleotide (NAD+) which regulates cellular energy metabolism …

Upregulation of exosomal microRNA‑21 in pancreatic stellate cells promotes pancreatic cancer cell migration and enhances Ras/ERK pathway activity

Q Ma, H Wu, Y Xiao, Z Liang… - … journal of oncology, 2020 - spandidos-publications.com
Pancreatic stellate cells (PSCs) are typically activated in pancreatic ductal adenocarcinoma
(PDAC) and release exosomes containing high levels of microRNA‑21 (miR‑21). However …

miR-211 regulates the expression of RRM2 in tumoral metastasis and recurrence in colorectal cancer patients with a k-ras gene mutation

CC Chang, CC Lin, CH Wang… - Oncology …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) ranks as the third‑leading cause of cancer‑associated mortalities in
Taiwan. The expression of ribonucleotide reductase M2 (RRM2) and p53R2 is associated …

Platinum-induced mitochondrial DNA mutations confer lower sensitivity to paclitaxel by impairing tubulin cytoskeletal organization

G Girolimetti, F Guerra, L Iommarini… - Human Molecular …, 2017 - academic.oup.com
Abstract Development of chemoresistance is a cogent clinical issue in oncology, whereby
combination of anticancer drugs is usually preferred also to enhance efficacy. Paclitaxel …

Tumor necrosis factor‐α− 308G/A and− 238G/A polymorphisms are associated with increased risks of sepsis: evidence from an updated meta‐analysis

M Zhang, Y Zhao, Q Liu - Apmis, 2017 - Wiley Online Library
Previous studies have reported the relationship between tumor necrosis factor‐α (TNF‐α)−
308G/A and− 238G/A polymorphisms and sepsis risk with inconsistent results. The aim of …

PI3K/Akt pathway and miR-21 are involved in N-ethyl-N-Nitrosourea-induced F1 mouse lung tumorigenesis: effect of inositol Hexaphosphate

S Sahay, P Tiwari, M Pandey… - Journal of Environmental …, 2019 - dl.begellhouse.com
The risk of cancer development in offspring due to carcinogen exposure during pregnancy is
a serious issue. In this study, we explored the involvement of the phosphatidylinositol 3 …

The Role of Nutrition in Cancer: From Cellular and Molecular Perspective

N Rasaei, A Ildarabadi, F Rahmani, F Shiravi… - 2024 - Springer
Cancer is a disease that disrupts the body's genetic composition, causing instability in the
genome. Moreover, despite notable progress in cancer treatment, the enduring global …

Differential microRNAs expression during cancer development, and chemoprevention by natural compounds: a comprehensive review.

C Pandey, P Tiwari - Journal of Environmental Pathology, Toxicology … - dl.begellhouse.com
MicroRNAs are short non-coding RNAs that inhibit gene expression at the post-
transcriptional level. Abnormal microRNA expression has been associated with different …

Anti-cancer Role of Ellagic Acid by Modulating the Altered PI3K/PTEN/Akt Pathway in Bladder Cancer

S Sahay, D Trehan, R Kumari, J Sharma… - Journal of … - dl.begellhouse.com
Bladder cancer (BCa) is approximately 4th most prevalent diagnosed cancer in men and is
three times less common in women. Therefore, identifying biomarkers, developing more …

[引用][C] 小分子RNA 在子宫内膜异位症中的研究进展

马志华, 高尚风 - 中国妇幼健康研究, 2016