The slow death of the concept of schizophrenia and the painful birth of the psychosis spectrum

S Guloksuz, J van Os - Psychological medicine, 2018 - cambridge.org
The concept of schizophrenia only covers the 30% poor outcome fraction of a much broader
multidimensional psychotic syndrome, yet paradoxically has become the dominant prism …

[HTML][HTML] Auditory verbal hallucinations and continuum models of psychosis: A systematic review of the healthy voice-hearer literature

D Baumeister, O Sedgwick, O Howes… - Clinical psychology review, 2017 - Elsevier
Recent decades have seen a surge of research interest in the phenomenon of healthy
individuals who experience auditory verbal hallucinations, yet do not exhibit distress or need …

[HTML][HTML] Shared and unique brain network features predict cognitive, personality, and mental health scores in the ABCD study

J Chen, A Tam, V Kebets, C Orban, LQR Ooi… - Nature …, 2022 - nature.com
How individual differences in brain network organization track behavioral variability is a
fundamental question in systems neuroscience. Recent work suggests that resting-state and …

Validity and utility of hierarchical taxonomy of psychopathology (HiTOP): I. Psychosis superspectrum

R Kotov, KG Jonas, WT Carpenter, MN Dretsch… - World …, 2020 - Wiley Online Library
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …

[HTML][HTML] Somatosensory-motor dysconnectivity spans multiple transdiagnostic dimensions of psychopathology

V Kebets, AJ Holmes, C Orban, S Tang, J Li, N Sun… - Biological …, 2019 - Elsevier
Background There is considerable interest in a dimensional transdiagnostic approach to
psychiatry. Most transdiagnostic studies have derived factors based only on clinical …

Emerging evidence for astrocyte dysfunction in schizophrenia

EC de Oliveira Figueiredo, C Calì, F Petrelli, P Bezzi - Glia, 2022 - Wiley Online Library
Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

Transdiagnostic dimensions of psychosis in the Bipolar‐Schizophrenia Network on Intermediate Phenotypes (B‐SNIP)

U Reininghaus, JR Böhnke… - World …, 2019 - Wiley Online Library
The validity of the classification of non‐affective and affective psychoses as distinct entities
has been disputed, but, despite calls for alternative approaches to defining psychosis …

Focus on psychosis

W Gaebel, J Zielasek - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
The concept of psychosis has been shaped by traditions in the concepts of mental disorders
during the last 170 years. The term “psychosis” still lacks a unified definition, but denotes a …

Identification of different MRI atrophy progression trajectories in epilepsy by subtype and stage inference

F Xiao, L Caciagli, B Wandschneider, D Sone… - Brain, 2023 - academic.oup.com
Artificial intelligence (AI)-based tools are widely employed, but their use for diagnosis and
prognosis of neurological disorders is still evolving. Here we analyse a cross-sectional …

Unlocking neural function with 3D in vitro models: A technical review of self-assembled, guided, and bioprinted brain organoids and their applications in the study of …

C D'Antoni, L Mautone, C Sanchini, L Tondo… - International Journal of …, 2023 - mdpi.com
Understanding the complexities of the human brain and its associated disorders poses a
significant challenge in neuroscience. Traditional research methods have limitations in …