Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Salt and cocrystal formation are the most commonly used method of increasing solubility
and dissolution rate of pharmaceutical compounds, and are of particular interest for …

Identification of lead compounds with higher molecular weight and lower aqueous solubility
has become increasingly prevalent with the advent of high throughput screening. Poor …

Seasonal influenza virus infections cause a substantial number of deaths each year. While
zanamivir (ZAN) is efficacious against oseltamivir-resistant influenza strains, the efficacy of …

Redox flow batteries (RFB) have emerged as one of the most promising technologies for
large‐scale energy storage owing to their high safety, long operation life, and decoupled …

This paper aimed to prepare a Mabuterol (MAB) patch for treating asthma by ion-pair
strategy to overcome the drug's thermal instability and elucidate the molecular mechanisms …

The purpose of this study was to enhance the delivery of Etodolac (ETD) to the brain through
intranasal administration using an ionic liquid (IL) consisting of ETD and proline ethyl ester …

The present study was undertaken to overcome the problems associated with solubility,
dissolution and oral bioavailability of a poorly water-soluble ionizable drug, telmisartan …

Etodolac (ETD) is a nonsteroidal anti-inflammatory drug (NSAID) approved by the United
States Food and Drug Administration (US-FDA) in 1991 for the treatment of rheumatoid …

Many small-molecule active pharmaceutical ingredients (APIs) exhibit low aqueous
solubility and benefit from generation of amorphous dispersions of the API and polymer to …