The liver metabolizes ethanol through three enzymatic pathways: alcohol dehydrogenase
(ADH), cytochrome p450 (also called MEOS), and catalase. Alcohol dehydrogenase class I …

In last decades, healthy aging has become one of research hotspots in life science. It is well
known that the nicotinamide adenine dinucleotide oxidized form (NAD+) level in cells …

In transfusion medicine, there has been a decades-long debate about whether the age of
stored red blood cells (RBCs) is a factor in transfusion efficacy. Existing clinical studies …

Pyruvate is the end product of glycolysis and transported into the mitochondria for use in the
tricarboxylic acid (TCA) cycle. It is also a common additive in cell culture media. We …

Type A lactic acidosis resulted from hypoxic mitochondrial dysfunction is an independent
predictor of mortality for critically ill patients. However, current therapeutic agents are still in …

Aim: To explore the potential therapeutic effect of yttrium oxide nanoparticles (Y2O3 NPs) on
fulminant hepatic failure. Materials & methods: RAW264. 7 cells and a lipopolysaccharide/D …

Acrylamide (AA), classified as a probable carcinogen, can be neurotoxic, genotoxic, and can
damage DNA. This study explored the ability of seabuckthorn berries juice (SBJ) to alleviate …

Background Massive transfusion with older packed red blood cells is associated with
increased morbidity and mortality. As packed red blood cells age, they undergo biochemical …

The development of red blood cell (RBC) storage lesion during hypothermic storage has
long posed challenges for blood transfusion efficacy. These alterations are primarily driven …

There have been ongoing debates about resuscitation fluids because each of the current
fluids has its own disadvantages. The debates essentially reflect an embarrassing clinical …