B cell and antibody repertoire development in rabbits: the requirement of gut-associated lymphoid tissues
RG Mage, D Lanning, KL Knight - Developmental & Comparative …, 2006 - Elsevier
The antibody repertoire of rabbits has interested immunologists for decades, in part because
of the ease with which large quantities of high affinity antibodies can be obtained in serum …
of the ease with which large quantities of high affinity antibodies can be obtained in serum …
An overview of the lagomorph immune system and its genetic diversity
Our knowledge of the lagomorph immune system remains largely based upon studies of the
European rabbit (Oryctolagus cuniculus), a major model for studies of immunology. Two …
European rabbit (Oryctolagus cuniculus), a major model for studies of immunology. Two …
[图书][B] Pulsed field gel electrophoresis: a practical guide
B Birren, E Lai - 2012 - books.google.com
Pulsed Field Gel Electrophoresis: A Practical Guide is the first laboratory manual to describe
the theory and practice of this technique. Based on the authors' experience developing …
the theory and practice of this technique. Based on the authors' experience developing …
Rabbit IgH sequences in appendix germinal centers: VH diversification by gene conversion-like and hypermutation mechanisms
PD Weinstein, AO Anderson, RG Maget - Immunity, 1994 - cell.com
Although the rabbit IgH locus contains approximately 100 VH genes, the majority of B cells
rearrange VHl. To produce a primary repertoire containing a sufficient number of protective …
rearrange VHl. To produce a primary repertoire containing a sufficient number of protective …
Generating the antibody repertoire in rabbit
KL Knight, MA Crane - Advances in immunology, 1994 - Elsevier
Publisher Summary This chapter discusses the rabbit B lymphoid system including B cell
ontogeny, immunoglobulin (Ig) gene organization and rearrangement, and development of …
ontogeny, immunoglobulin (Ig) gene organization and rearrangement, and development of …
Generation and regeneration of cells of the B-lymphocyte lineage
A Rolink, F Melchers - Current opinion in immunology, 1993 - Elsevier
B lymphopoiesis in the mouse and in man can be divided into two phases, one in which the
compartments of the B lineage are filled with cells, and a second in which these …
compartments of the B lineage are filled with cells, and a second in which these …
Sequence analysis of 0.5 Mb of the rabbit germline immunoglobulin heavy chain locus
F Ros, J Puels, N Reichenberger, W van Schooten… - Gene, 2004 - Elsevier
A bacterial artificial chromosome (BAC) library was created using partially digested rabbit
chromosomal DNA. Four BAC clones spanning about 0.5 Mb of the rabbit immunoglobulin …
chromosomal DNA. Four BAC clones spanning about 0.5 Mb of the rabbit immunoglobulin …
Rabbit appendix: a site of development and selection of the B cell repertoire
R Pospisil, RG Mage - Somatic Diversification of Immune Responses, 1998 - Springer
The normal rabbit primarily rearranges a single (VH 1) gene to several DH and JH genes
(Becker et al. 1990; Knight and Becker 1990; Allegrucci et al. 1991). Thus combinatorial …
(Becker et al. 1990; Knight and Becker 1990; Allegrucci et al. 1991). Thus combinatorial …
Molecular bases of genetic diversity and evolution of the immunoglobulin heavy chain variable region (IGHV) gene locus in leporids
A Pinheiro, D Lanning, PC Alves, RG Mage, KL Knight… - Immunogenetics, 2011 - Springer
The rabbit has long been a model for studies of the immune system. Work using rabbits
contributed both to the battle against infectious diseases such as rabies and syphilis, and to …
contributed both to the battle against infectious diseases such as rabies and syphilis, and to …
Preferential expansion and survival of B lymphocytes based on VH framework 1 and framework 3 expression:" positive" selection in appendix of normal and VH …
R Pospisil, GO Young-Cooper… - Proceedings of the …, 1995 - National Acad Sciences
B cells with a rearranged heavy-chain variable region VHa allotype-encoding VH1 gene
segment predominate throughout the life of normal rabbits and appear to be the source of …
segment predominate throughout the life of normal rabbits and appear to be the source of …