The wiring of developing sensory circuits—from patterned spontaneous activity to synaptic plasticity mechanisms
AH Leighton, C Lohmann - Frontiers in neural circuits, 2016 - frontiersin.org
In order to accurately process incoming sensory stimuli, neurons must be organized into
functional networks, with both genetic and environmental factors influencing the precise …
functional networks, with both genetic and environmental factors influencing the precise …
Spatiotemporal features of retinal waves instruct the wiring of the visual circuitry
DA Arroyo, MB Feller - Frontiers in neural circuits, 2016 - frontiersin.org
Coordinated spontaneous activity is present in different sensory systems during early stages
of development. This activity is thought to play a critical role in the development of sensory …
of development. This activity is thought to play a critical role in the development of sensory …
An excitatory cortical feedback loop gates retinal wave transmission in rodent thalamus
Y Murata, MT Colonnese - Elife, 2016 - elifesciences.org
Spontaneous retinal waves are critical for the development of receptive fields in visual
thalamus (LGN) and cortex (VC). Despite a detailed understanding of the circuit …
thalamus (LGN) and cortex (VC). Despite a detailed understanding of the circuit …
Activity-dependent development of visual receptive fields
Highlights•Molecular cues and activity together shape visual circuit development.•Activity
influences development at all levels of the visual system.•Before vision, activity is generated …
influences development at all levels of the visual system.•Before vision, activity is generated …
Spontaneous retinal waves can generate long-range horizontal connectivity in visual cortex
In the primary visual cortex (V1) of higher mammals, long-range horizontal connections
(LHCs) are observed to develop, linking iso-orientation domains of cortical tuning. It is …
(LHCs) are observed to develop, linking iso-orientation domains of cortical tuning. It is …
meaRtools: An R package for the analysis of neuronal networks recorded on microelectrode arrays
Here we present an open-source R package 'meaRtools' that provides a platform for
analyzing neuronal networks recorded on Microelectrode Arrays (MEAs). Cultured neuronal …
analyzing neuronal networks recorded on Microelectrode Arrays (MEAs). Cultured neuronal …
Glutamatergic retinal waves
D Kerschensteiner - Frontiers in neural circuits, 2016 - frontiersin.org
Spontaneous activity patterns propagate through many parts of the developing nervous
system and shape the wiring of emerging circuits. Prior to vision, waves of activity originating …
system and shape the wiring of emerging circuits. Prior to vision, waves of activity originating …
An evolving view of retinogeniculate transmission
EY Litvina, C Chen - Visual neuroscience, 2017 - cambridge.org
The thalamocortical (TC) relay neuron of the dorsoLateral Geniculate Nucleus (dLGN) has
borne its imprecise label for many decades in spite of strong evidence that its role in visual …
borne its imprecise label for many decades in spite of strong evidence that its role in visual …
Development of functional properties in the early visual system: new appreciations of the roles of lateral geniculate nucleus
AK Stacy, SD Van Hooser - Sensitive Periods of Brain Development and …, 2022 - Springer
In the years following Hubel and Wiesel's first reports on ocular dominance plasticity and
amblyopia, much attention has been focused on understanding the role of cortical circuits in …
amblyopia, much attention has been focused on understanding the role of cortical circuits in …
Balanced enhancements of synaptic excitation and inhibition underlie developmental maturation of receptive fields in the mouse visual cortex
Neurons in the developing visual cortex undergo progressive functional maturation as
indicated by the refinement of their visual feature selectivity. However, changes of the …
indicated by the refinement of their visual feature selectivity. However, changes of the …