Deep eutectic solvents: Recent advances in fabrication approaches and pharmaceutical applications

Y Liu, Y Wu, J Liu, W Wang, Q Yang, G Yang - International Journal of …, 2022 - Elsevier
Deep eutectic solvents (DESs) have received increasing attention in the past decade owing
to their distinguished properties including biocompatibility, tunability, thermal and chemical …

Overview and thermodynamic modelling of deep eutectic solvents as co-solvents to enhance drug solubilities in water

A Zarei, R Haghbakhsh, S Raeissi - European Journal of Pharmaceutics …, 2023 - Elsevier
The poor water solubility of active pharmaceutical ingredients (APIs) is a major challenge in
the pharmaceutical industry. Co-solvents are sometimes added to enhance drug dissolution …

A feasibility study on the use of hydrophobic eutectic solvents as pseudo-stationary phases in capillary electrophoresis for chiral separations

A Li, S Xue, Y Xu, S Ding, D Wen, Q Zhang - Analytica Chimica Acta, 2023 - Elsevier
A critical challenge in using deep eutectic solvents (DESs) in capillary electrophoresis (CE)
is to develop separation systems in which a DES can really work as a single entity. To …

Chiral separation by capillary electrokinetic chromatography with hydrophobic deep eutectic solvents as pseudo-stationary phases

Y Xu, A Li, S Xue, S Ding, Q Zhang - Talanta, 2023 - Elsevier
This study demonstrated for the first time that hydrophobic deep eutectic solvents (HDESs)
can be used in capillary electrophoresis (CE) for chiral separations. We found that the an …

Application of deep eutectic solvents (DESs) as trace level drug extractants and drug solubility enhancers: State-of-the-art, prospects and challenges

W Lu, H Chen - Journal of Molecular Liquids, 2022 - Elsevier
Deep eutectic solvents (DESs) have garnered substantial interest from the scientific
community in recent years due to their widely recognized potential as green alternatives to …

Novel protic ionic liquids-based phase change materials for high performance thermal energy storage systems

M Mokhtarpour, A Rostami, H Shekaari, A Zarghami… - Scientific Reports, 2023 - nature.com
Phase change materials (PCMs) are an important class of innovative materials that
considerably contribute to the effective use and conservation of solar energy and wasted …

Deep eutectic systems as novel vehicles for assisting drug transdermal delivery

J Wang, M Li, L Duan, Y Lin, X Cui, Y Yang, C Wang - Pharmaceutics, 2022 - mdpi.com
In recent years, deep eutectic systems (DES) emerged as novel vehicles for facilitating the
transdermal delivery of various drugs, including polysaccharides, proteins, insulin, vaccine …

Choline-based deep eutectic solvent combined with EDTA-2Na as novel soil washing agent for lead removal in contaminated soil

K Huang, Y Shen, X Wang, X Song, W Yuan, J Xie… - Chemosphere, 2021 - Elsevier
Lead-contaminated soil was cleaned through ethylene-diamine-teraacetic acid disodium
salt (EDTA-2Na) combined with diluted deep eutectic solvent (DES) which was prepared by …

Solubility of mesalazine in aqueous solutions of two betaine-based deep eutectic solvents at different temperatures: Data correlation and thermodynamic analysis

P Jafari, M Barzegar-Jalali, A Jouyban - Journal of Molecular Liquids, 2022 - Elsevier
Temperature-dependent solubility data for mesalazine in the cosolvency systems composed
of water and deep eutectic solvents (DESs) obtained from betaine as a hydrogen bond …

Photocatalytic degradation of acetaminophen in aqueous environments: a mini review

Z Wang, H Chen, C Rong, A Li, X Hua, D Dong… - Toxics, 2023 - mdpi.com
Over the past few decades, acetaminophen (ACT), a typical nonsteroidal anti-inflammatory
drug (NSAID), has gained global usage, positioning itself as one of the most extensively …