The extracellular matrix (ECM) is a highly complex structure through which biochemical and
mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a …

The mechanical properties of cells and tissues help determine their architecture,
composition and function. Alterations to these properties are associated with many diseases …

Bladder mechanical properties are critical for organ function and tissue homeostasis.
Therefore, alterations of tissue mechanics are linked to disease onset and progression. This …

Atomic Force Microscopy (AFM) is successfully used for the quantitative investigation of the
cellular mechanosensing of the microenvironment. To this purpose, several force …

High-risk non-muscle-invasive bladder cancer (NMIBC) presents high recurrence and
progression rates. Despite the use of Bacillus Calmette-Guérin gold-standard …

Fibrillar collagen accumulation emerges as a promising biomarker in several diseases, such
as desmoplastic tumors and unstable atherosclerotic plaque. Gold nanorods (GNRs) hold …

The deformability and uptake capability of cells are critical indicators of their biomechanical
properties and functional behaviors, particularly in tumor heterogeneity and cancer …

During cancer metastasis, cancer cells will encounter various microenvironments with
diverse physical characteristics. Changes in these physical characteristics such as tension …

Background Non-muscle invasive bladder cancer (NMIBC) patients are affected by a high
risk of recurrence. The topography of collagen fibers represents a hallmark of the neoplastic …

Malignancies of epithelial tissues, called carcinomas, account for most cancer cases.
Research has largely focused on correlating different carcinoma subtypes to genetic …