The life cycle of malaria parasites in both their mammalian host and mosquito vector
consists of multiple developmental stages that ensure proper replication and progeny …

Gametocytes and sporozoites must both overcome similar obstacles. After fully maturing,
they must lie in wait and be prepared for a fleeting moment when a mosquito takes a blood …

Abstract Metallo-beta-lactamase (MBL) is a class of enzyme that catalyzes the hydrolysis of
a broad range of beta-lactam antibiotics leading to the development of drug resistance in …

Plasmodium sporozoites are the infective forms of the malaria parasite in the mosquito and
vertebrate host. Gliding motility allows sporozoites to migrate and invade mosquito salivary …

Malaria parasite transmission to humans is initiated by the inoculation of Plasmodium
sporozoites into the skin by mosquitoes. Sporozoites develop within mosquito midgut …

During transmission of malaria‐causing parasites from mosquitoes to mammals,
Plasmodium sporozoites migrate rapidly in the skin to search for a blood vessel. The high …

Malaria parasites must respond quickly to environmental changes, including during their
transmission between mammalian and mosquito hosts. Therefore, female gametocytes …

Background Plasmodium sporozoites are the highly motile forms of malaria-causing
parasites that are transmitted by the mosquito to the vertebrate host. Sporozoites need to …

The nuclear pore complex (NPC) is a large macromolecular assembly of around 30 different
proteins, so-called nucleoporins (Nups). Embedded in the nuclear envelope the NPC …

Although much progress has been made in the fight against malaria, the number of people
that contract this disease due to the bite of an Anopheline mosquito remains unacceptably …