Copper is a critical metal nutrient required by marine microalgae but may be toxic when
supplied in excess. Maintaining an optimal intracellular Cu content is thus fundamentally …

Uricase (urate: oxygen oxidoreductase, EC␣ 1.7. 3.3) from leaves of chickpea (Cicer
arietimum L.), broad bean (Vicia faba major L.), and wheat (Triticum aestivum L.) has been …

Nitrogen is available in the environment in different redox states and in a wide variety of
nitrogenous compounds. Algal cells are capable of assimilating nitrogen from many of these …

Copper (Cu) chaperones, of which yeast ATX1 is a prototype, are small proteins with a Cu (I)
binding MxCxxC motif and are responsible for directing intracellular Cu toward specific client …

Uricase (urate: oxygen oxidoreductase; EC 1.7. 3.3) from bean (Phaseolusvulgaris) leaves
and uredospores of two different rust fungi (Uromyces phaseoli and Uromyces fabae) has …

Gout, marked by the deposition of sodium urate crystals in joints and peripheral tissues,
presents a considerable health challenge. Recent research has shown a growing interest in …

The peroxisomal enzyme urate oxidase plays a pivotal role in the degradation of purines in
both prokaryotes and eukaryotes. However, knowledge about the purine‐induced …

Uric acid (UA) deposition in human body is very harmful, since it may induce gout.
Therefore, it would be of great significance to catalyze the degradation of UA in human body …

The clinical utilization of Uricase against gout is limited due to the immunogenicity. In the
present article, we identified the antigenic determinants of Uricase and reduced their …

Hyperuricemia and its symptoms are becoming increasingly common worldwide. Elevated
serum uric acid levels are caused by increased uric acid synthesis from food constituents …