Abstract Changes in environmental conditions can rapidly shift allele frequencies in
populations of species with relatively short generation times. Frequency shifts might be …

Genetic mapping in natural populations is increasing rapidly in feasibility and accessibility.
As with many areas in genetics, advances in molecular techniques and statistics are …

Understanding how and why populations evolve is of fundamental importance to molecular
ecology. Restriction site‐associated DNA sequencing (RAD seq), a popular reduced …

We report genome sequences of 17 inbred strains of laboratory mice and identify almost ten
times more variants than previously known. We use these genomes to explore the …

Next-generation sequencing technology provides novel opportunities for gathering genome-
scale sequence data in natural populations, laying the empirical foundation for the evolving …

Heterogametic sex chromosomes have evolved independently in various lineages of
vertebrates. Such sex chromosome pairs often contain nonrecombining regions, with one of …

The identification of precise mutations is required for a complete understanding of the
underlying molecular and evolutionary mechanisms driving adaptive phenotypic change …

The house mouse, Mus musculus, was established in the early 1900s as one of the first
genetic model organisms owing to its short generation time, comparatively large litters, ease …

Adaptation is a central focus of biology, although it can be difficult to identify both the
strength and agent of selection and the underlying molecular mechanisms causing change …

Single nucleotide polymorphisms (SNPs), genotyped with arrays, have become a widely
used marker type in population genetic analyses over the last 10 years. However, compared …