This article provides the first extensive documentation of the dose response features of pre-
and postconditioning. Pre-and postconditioning studies with rigorous study designs, using …

Optimal perioperative oxygen administration : Current Opinion in Anesthesiology Optimal
perioperative oxygen administration : Current Opinion in Anesthesiology Log in or Register …

Objective: Epidemiologic studies showed an association between adverse intrauterine
environment and ischemic heart disease in the adult. We tested the hypothesis that prenatal …

Abstract The heme oxygenase-1 (Hmox1; HO-1) pathway was tested for defense of
mitochondrial quality control in cardiomyocyte-specific Hmox1 KO mice (HO-1 [CM]–/–) …

The current practice of mechanical ventilation comprises the use of the least inspiratory O 2
fraction associated with an arterial O 2 tension of 55 to 80 mm Hg or an arterial hemoglobin …

CCN2/connective tissue growth factor (CTGF), a CCN family matricellular protein repressed
in healthy hearts after birth, is induced in heart failure of various etiologies. Multiple cellular …

Purpose Data on the benefit or or harmful effects of oxygen level on ischemic reperfusion
injuries in cardiac surgery are insufficient. We hypothesized that hyperoxia during …

Objective: The relative contributions of the fraction of inspired oxygen (FIO2) and
atmospheric pressure (ATM) to cardioprotection are unknown. We determined whether the …

Supplemental oxygen (O 2) is used as adjunct therapy in anesthesia, emergency, and
intensive care medicine. We hypothesized that excessive O 2 levels (hyperoxia) can directly …

Objective: Inhalation of oxygen improves the hemodynamic status and attenuates the
inflammatory response after intestinal ischemia-reperfusion (IR). Yet, the use of hyperoxia is …