Though initially described in the early 1960s, it is only within the past decade that the
concept of continuing adult neurogenesis has gained widespread acceptance. Neuroblasts …

The basic Helix-Loop-Helix (bHLH) proteins represent a well-known class of transcriptional
regulators. Many bHLH proteins act as heterodimers with members of a class of ubiquitous …

Neuroinflammation is a well-characterized pathophysiology occurring in association with the
progression of Parkinson's disease. Characterizing the cellular and molecular basis of …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-
motor symptoms and loss of dopaminergic neurons of the substantia nigra. Inflammation and …

The neural crest (NC) is a transient multipotent cell population that originates in the dorsal
neural tube. Cells of the NC are highly migratory, as they travel considerable distances …

Adult stem cells are important for tissue turnover and regeneration. However, in most adult
systems it remains elusive how stem cells assume different functional states and support …

Comprehensive Overview of Advances in OlfactionThe common belief is that human smell
perception is much reduced compared with other mammals, so that whatever abilities are …

During the preimplantation stage, mouse embryos establish two cell lineages by the time of
early blastocyst formation: the trophectoderm (TE) and the inner cell mass (ICM). Historical …

Neurons in the mammalian central nervous system display an enormous capacity for circuit
formation during development but not later in life. In principle, new circuits could be also …

Adult neural stem/precursor cells (NSPC s) of the subventricular zone (SVZ) are an
endogenous source for neuronal replacement in CNS disease. However, adult …