[HTML][HTML] Structure-activity-relationship and mechanistic insights for anti-HIV natural products

R Kaur, P Sharma, GK Gupta, F Ntie-Kang, D Kumar - Molecules, 2020 - mdpi.com
Acquired Immunodeficiency Syndrome (AIDS), which chiefly originatesfroma retrovirus
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …

A comprehensive review of N-heterocycles as cytotoxic agents

D Kumar, S Kumar Jain - Current Medicinal Chemistry, 2016 - ingentaconnect.com
Scientific community is striving to understand the role of heterocycles and fused
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …

[HTML][HTML] Natural product-based studies for the management of castration-resistant prostate cancer: Computational to clinical studies

RK Singla, P Sharma, AK Dubey… - Frontiers in …, 2021 - frontiersin.org
Background: With prostate cancer being the fifth-greatest cause of cancer mortality in 2020,
there is a dire need to expand the available treatment options. Castration-resistant prostate …

[HTML][HTML] The role of nanomaterials in enhancing natural product translational potential and modulating endoplasmic reticulum stress in the treatment of ovarian cancer

RK Singla, P Sharma, D Kumar, RK Gautam… - Frontiers in …, 2022 - frontiersin.org
Ovarian cancer, and particularly its most frequent type, epithelial ovarian carcinoma,
constitutes one of the most dangerous malignant tumors among females. Substantial …

[HTML][HTML] Phytochemical and Ethnopharmacological Perspectives of Ehretia laevis

P Sharma, R Shri, F Ntie-Kang, S Kumar - Molecules, 2021 - mdpi.com
Ehretia laevis Roxb.(Boraginaceae) has been extensively used as a traditional remedy for
the treatment of a diverse range of ailments related to the respiratory system, the …

Mechanistic insights and docking studies of phytomolecules as potential candidates in the management of cancer

P Sharma, D Kumar, R Shri… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Background: Cancer is a leading risk of death globally. According to the World Health
Organization, it is presently the second most important disease that causes death in both …

Phytochemistry and Polypharmacological Potential of Colebrookea oppositifolia Smith

D Kumar, RK Singla, P Sharma, L Kumar… - Current Topics in …, 2023 - ingentaconnect.com
Background: Colebrookea oppositifolia Smith. is a valuable traditional therapeutic plant
belonging to the family Lamiaceae. It is a dense and wool-like shrub that is mostly found in …

[PDF][PDF] Treatment of tuberculosis by natural drugs: A review

T Kaur, P Sharma, GK Gupta, F Ntie-Kang, D Kumar - Plant Arch, 2019 - researchgate.net
Tuberculosis is a serious infectious bacterial disease. The disease is highly contagious and
mostly transmitted from person to person, usually by bacteria and it is mostly transmitted by …

Purine analogues as kinase inhibitors: a review

S Sharma, S Mehndiratta, S Kumar… - Recent Patents on …, 2015 - ingentaconnect.com
Protein kinases constitute one of the largest and most functionally diverse gene families that
regulate key cell functions. In past several years, kinase inhibition has emerged as potential …

[HTML][HTML] In search of therapeutic candidates for HIV/AIDS: rational approaches, design strategies, structure–activity relationship and mechanistic insights

D Kumar, P Sharma, R Kaur, MMM Lobe, GK Gupta… - RSC …, 2021 - pubs.rsc.org
The HIV/AIDS pandemic is a serious threat to the health and development of mankind, which
has affected about 37.9 million people worldwide. The increasing negative health, economic …