[HTML][HTML] The role of N6-methyladenosine modification in rodent models of neuropathic pain: from the mechanism to therapeutic potential

L Wu, H Tang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Neuropathic pain (NP) is a common chronic pain condition resulted from lesions or diseases
of somatosensory nervous system, but the pathogenesis remains unclear. A growing body of …

RNA‐binding proteins in pain

PR Smith, ZT Campbell - Wiley Interdisciplinary Reviews: RNA, 2024 - Wiley Online Library
RNAs are meticulously controlled by proteins. Through direct and indirect associations,
every facet in the brief life of an mRNA is subject to regulation. R NA‐b inding p roteins …

Low molecular weight inhibitors targeting the RNA-binding protein HuR

BP Joseph, V Weber, L Knüpfer, A Giorgetti… - International journal of …, 2023 - mdpi.com
The RNA-binding protein human antigen R (HuR) regulates stability, translation, and
nucleus-to-cytoplasm shuttling of its target mRNAs. This protein has been progressively …

The Role and Mechanism of RNA-binding Proteins in Bone Metabolism and Osteoporosis

J Wu, L Niu, K Yang, J Xu, D Zhang, J Ling, P Xia… - Ageing Research …, 2024 - Elsevier
Osteoporosis is a prevalent chronic metabolic bone disease that poses a significant risk of
fractures or mortality in elderly individuals. Its pathophysiological basis is often attributed to …

[HTML][HTML] Protocol for the isolation and culture of mouse dorsal root ganglion neurons for imaging applications

PR Smith, A Meyer, S Loerch, ZT Campbell - STAR protocols, 2023 - Elsevier
Sensory neurons play pervasive roles throughout biology. In vitro studies to probe their
functions hinge on the successful application of primary cell culture. Here, we present a …

Development of novel analgesics: targeting the RNA-binding protein HuR

BP Joseph, M Albrecht, P Carloni, G Rossetti - 2024 - publications.rwth-aachen.de
In dieser Arbeit wird die Funktion des RNA-bindenden humanen Antigen R Proteins (HuR)
und seine Arzneitauglichkeit mithilfe computergestützter Methoden untersucht. HuR reguliert …

Novel Modes of Translational Regulation by eEF2K in the Peripheral Nervous System

PR Smith - 2024 - search.proquest.com
Translation–the process of decoding messenger RNA and synthesizing proteins–lies at the
core of biology. Eukaryotes have evolved myriad mechanisms to control the timing, location …