Importance Type 2 diabetes is associated with increased cardiovascular risk. In placebo-
controlled cardiovascular safety trials, the dipeptidyl peptidase-4 inhibitor linagliptin …

Diabetes has become a major burden of healthcare expenditure. Diabetes management
following a uniform treatment algorithm is often associated with progressive treatment failure …

Type 2 diabetes mellitus (T2DM) is the most common form of diabetes, and is rising in
incidence with widespread prevalence. Multiple gene variants are associated with glucose …

Personalized medicine aims at better targeting therapeutic intervention to the individual to
maximize benefit and minimize harm. Type 2 diabetes (T2D) is a heterogeneous disease …

Summary Transcription factor 7‐like 2 (TCF7L2), a member of the T cell factor/lymphoid
enhancer factor family, generally forms a complex with β‐catenin to regulate the …

Type 2 diabetes mellitus (T2DM) is recognized as a public health problem and increasingly
prevalent illness. Key elements of the guideline for diabetes care are based on evidence …

Purpose Type 2 diabetes mellitus (T2DM) has a high global prevalence, and the interaction
of environmental factors and genetic factors may contribute to the risk of T2DM. We aimed to …

Mexico has been under official epidemiological alert due to diabetes since 2016. This study
presents new information on the frequency and variants of metformin transporters OCT1 …

Background: Type 2 Diabetes Mellitus (T2DM) is a worldwide disorder as the most important
challenges of health-care systems. Controlling the normal glycaemia greatly profit long-term …

Type 2 diabetes prevalence is still on the rise worldwide. Antidiabetic drugs are widely
prescribed to patients with Type 2 diabetes. Most patients start with metformin which is …