Differences in neurotoxic outcomes of organophosphorus pesticides revealed via multi-dimensional screening in adult and regenerating planarians

D Ireland, S Zhang, V Bochenek, JH Hsieh… - Frontiers in …, 2022 - frontiersin.org
Organophosphorus pesticides (OPs) are a chemically diverse class of commonly used
insecticides. Epidemiological studies suggest that low dose chronic prenatal and infant …

Screening for neurotoxic potential of 15 flame retardants using freshwater planarians

S Zhang, D Ireland, NS Sipes, M Behl… - Neurotoxicology and …, 2019 - Elsevier
Asexual freshwater planarians are an attractive invertebrate model for high-throughput
neurotoxicity screening, because they possess multiple quantifiable behaviors to assess …

Chemical Exposure-Induced Developmental Neurotoxicity in Head-Regenerating Schmidtea mediterranea

J Morris, EJ Bealer, IDS Souza, L Repmann… - Toxicological …, 2022 - academic.oup.com
The growing number of commercially used chemicals that are under-evaluated for
developmental neurotoxicity (DNT) combined with the difficulty in describing the etiology of …

[HTML][HTML] Planarian fragments behave as whole animals

D Le, Z Sabry, A Chandra, WB Kristan, EMS Collins - Current Biology, 2021 - cell.com
Behavioral responses of freshwater planarians have been studied for over a century. 1 In
recent decades, behavior has been used as a readout to study planarian development and …

Pharmacological or genetic targeting of Transient Receptor Potential (TRP) channels can disrupt the planarian escape response

Z Sabry, A Ho, D Ireland, C Rabeler… - PLoS …, 2019 - journals.plos.org
In response to noxious stimuli, planarians cease their typical ciliary gliding and exhibit an
oscillatory type of locomotion called scrunching. We have previously characterized the …

Planarian scrunching as a quantitative behavioral readout for noxious stimuli sensing

Z Sabry, C Rabeler, D Ireland, K Bayingana… - JoVE (Journal of …, 2020 - jove.com
Freshwater planarians normally glide smoothly through ciliary propulsion on their ventral
side. Certain environmental conditions, however, can induce musculature-driven forms of …

Quantifying planarian behavior as an introduction to object tracking and signal processing

NC Stowell, T Goel, V Shetty, J Noveral… - The …, 2021 - meridian.allenpress.com
Answers to mechanistic questions about biological phenomena require fluency in a variety
of molecular biology techniques and physical concepts. Here, we present an …

Measuring functional brain recovery in regenerating planarians by assessing the behavioral response to the cholinergic compound cytisine

OR Pagán, DL Baker, S Deats… - International …, 2020 - digitalcommons.wcupa.edu
Planarians are traditional model invertebrates in regeneration and developmental biology
research that also display a variety of quantifiable behaviors useful to screen for …

Molecular characterization of a flatworm Girardia isolate from Guanajuato, Mexico

EM Duncan, SH Nowotarski… - Developmental …, 2022 - Elsevier
Planarian flatworms are best known for their impressive regenerative capacity, yet this trait
varies across species. In addition, planarians have other features that share morphology …

A new species of planarian flatworm from Mexico: Girardia guanajuatiensis

EM Duncan, SH Nowotarski, C Guerrero-Hernández… - bioRxiv, 2020 - biorxiv.org
Background Planarian flatworms are best known for their impressive regenerative capacity,
yet this trait varies across species. In addition, planarians have other features that share …