A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …

Serotonin is an important gastrointestinal signaling molecule. It is a paracrine messenger
utilized by enterochromaffin (EC) cells, which function as sensory transducers. Serotonin …

The gastrointestinal tract is innervated by several distinct populations of neurons, whose cell
bodies either reside within (intrinsic) or outside (extrinsic) the gastrointestinal wall. Normally …

Inflammatory bowel diseases (IBDs) are chronic relapsing and remitting conditions
associated with long-term gut dysfunction resulting from alterations to the enteric nervous …

The enteric nervous system (ENS) of the gastrointestinal (GI) tract interacts with the local
immune system bidirectionally. Recent publications have demonstrated that such …

The focus of neurogastroenterology in Rome II was the enteric nervous system (ENS). To
avoid duplication with Rome II, only advances in ENS neurobiology after Rome II are …

Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of
the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease …

Abstract Knowledge of neural circuits, neurotransmitters and receptors involved in the
sympathetic regulation of gastrointestinal (GI) function is well established. However, it is only …

The intestinal epithelial barrier is the largest exchange surface between the body and the
external environment. Its functions are regulated by luminal, and also internal, components …

Recent research has highlighted the importance of the two-way interaction between the
nervous and immune systems. This interaction is particularly important in the bowel because …