Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …

The 28 mammalian members of the super-family of transient receptor potential (TRP)
channels are cation channels, mostly permeable to both monovalent and divalent cations …

In the nervous system, many intracellular responses to elevated calcium are mediated by
CaM kinases (CaMKs), a family of protein kinases whose activities are initially modulated by …

Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …

An increasing number of genetic variants have been implicated in autism spectrum
disorders (ASDs), and the functional study of such variants will be critical for the elucidation …

The transient receptor potential (TRP) ion channels are named after the discovery of the
photo-transducted channels in Drosophila. TRPs, activated by various extracellular and …

The existence of a mammalian family of TRPC ion channels, direct homologues of TRP, the
visual transduction channel of flies, was discovered during 1995–1996 as a consequence of …

Mushroom dendritic spine structures are essential for memory storage and the loss of
mushroom spines may explain memory defects in aging and Alzheimer9s disease (AD). The …

Depression is a common mental illness, which is related to monoamine neurotransmitters
and the dysfunction of the cholinergic, immune, glutamatergic, and neuroendocrine systems …

Electrical stimulation (ES)-triggered up-regulation of brain-derived neurotrophic factor
(BDNF) and neurite outgrowth in cultured rat postnatal dorsal root ganglion neurons …