Invited review: bacterial lipopolysaccharides and innate immunity

C Alexander, ET Rietschel - Journal of endotoxin research, 2001 - journals.sagepub.com
Bacterial lipopolysaccharides (LPS) are the major outer surface membrane components
present in almost all Gram-negative bacteria and act as extremely strong stimulators of …

Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock

ES Van Amersfoort, TJC Van Berkel… - Clinical microbiology …, 2003 - Am Soc Microbiol
Bacterial sepsis and septic shock result from the overproduction of inflammatory mediators
as a consequence of the interaction of the immune system with bacteria and bacterial wall …

Soil chemical insights provided through vibrational spectroscopy

SJ Parikh, KW Goyne, AJ Margenot, FND Mukome… - Advances in …, 2014 - Elsevier
Vibrational spectroscopy techniques provide a powerful approach to the study of
environmental materials and processes. These multifunctional analytical tools can be used …

[HTML][HTML] Lipopolysaccharide structure and the phenomenon of low endotoxin recovery

A Gorman, AP Golovanov - European Journal of Pharmaceutics and …, 2022 - Elsevier
Lipopolysaccharide (LPS) is a cell-wall component of Gram-negative bacteria which
contributes to bacterial toxicity. During processes such as cell division, shedding of outer …

Intrinsic conformation of lipid A is responsible for agonistic and antagonistic activity

U Seydel, M Oikawa, K Fukase… - European Journal of …, 2000 - Wiley Online Library
Lipopolysaccharides (LPS, endotoxin) represent a major virulence factor of Gram‐negative
bacteria, which can cause septic shock in mammals, including man. The lipid anchor of LPS …

A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins

AD Ferguson, W Welte, E Hofmann, B Lindner, O Holst… - Structure, 2000 - cell.com
Abstract Background: Lipopolysaccharide (LPS), a lipoglycan from the outer membrane of
Gram-negative bacteria, is an immunomodulatory molecule that stimulates the innate …

The charge of endotoxin molecules influences their conformation and IL-6-inducing capacity

AB Schromm, K Brandenburg, H Loppnow… - The Journal of …, 1998 - journals.aai.org
The activation of cells by endotoxin (LPS) is one of the early host responses to infections
with Gram-negative bacteria. The lipid A part of LPS molecules is known to represent the …

[图书][B] Endotoxins: pyrogens, LAL testing and depyrogenation

KL Williams - 2007 - books.google.com
This source expertly examines the discovery, biological structure, control, and continued
clarification of endotoxin from a parenteral manufacturing perspective, with in-depth …

Biophysical characterization of lipopolysaccharide and lipid A inactivation by lactoferrin

K Brandenburg, G Jürgens, M Müller, S Fukuoka… - 2001 - degruyter.com
The interaction of bacterial endotoxins (LPS Re and lipid A, the endotoxic principle of LPS)
with the endogenous antibiotic lactoferrin (LF) was investigated using various physical …

New insights into endotoxin-induced activation of macrophages: involvement of a K+ channel in transmembrane signaling

R Blunck, O Scheel, M Müller… - The Journal of …, 2001 - journals.aai.org
LPS (endotoxins) activate cells of the human immune system, among which are monocytes
and macrophages, to produce endogenous mediators. These regulate the immune …