Heterocyclic modulators of hif activity for treatment of disease

P Jones, ME DiFrancesco, A Petrocchi… - US Patent App. 13 …, 2014 - Google Patents
2013-10-10 Assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
reassignment BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM ASSIGNMENT …

Derivatives of pyridone and the use of them

X Yi - US Patent 7,825,133, 2010 - Google Patents
US PATENT DOCUMENTS WO WOO1, 58.448 A1 8, 2001 WO WO 2005/047256 A1 5, 2005
2006/010O249 A1 5, 2006 Smith WO WO 2006/004100 A1 1/2006 2006/01 10358 A1 5 …

Compounds and methods for treating inflammatory and fibrotic disorders

K Kossen, SD Seiwert, V Serebryany… - US Patent …, 2012 - Google Patents
2009-08-04 Assigned to INTERMUNE, INC. reassignment INTERMUNE, INC. ASSIGNMENT
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HU, TAO …

New pyridone derivates with mch antagonistic activity and medicaments comprising these compounds

D Stenkamp, SG Mueller, GJ Roth, J Kley… - US Patent App. 13 …, 2012 - Google Patents
JHEXLSJTUGDZBS-UHFFFAOYSA-N CN1CCC2= C (C= C (C (= O) CN3N= CC (OCC4=
CC= CC= C4)= CC3= O) C= C2) C1 Chemical compound CN1CCC2= C (C= C (C (= O) …

Amine derivative compounds for treating ophthalmic diseases and disorders

IL Scott, VA Kuksa, MW Orme, F Hong, TL Little… - US Patent …, 2013 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
40097866&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Substituted pyridazines as EGFR and/or KRAS inhibitors

H Djaballah, HE Varmus, D Shum, R Somwar… - US Patent …, 2017 - Google Patents
The present invention is directed to pyridaZinone com pounds of formula (I) and furan
compounds of formula (II), pharmaceutical compositions of compounds of formula (I) and (II) …

Anti-fibrotic pyridinones

BO Buckman, JB Nicholas, JY Ramphal… - US Patent …, 2016 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
50435378&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Methyl/fluoro-pyridinyl-methoxy substituted pyridinone-pyridinyl compounds and fluoro-pyrimidinyl-methoxy substituted pyridinone-pyridinyl compounds

SL Hockerman, JB Monahan, SR Selness - US Patent 9,636,333, 2017 - Google Patents
The present disclosure provides methyl/fluoro-pyridinyl methoxy Substituted pyridinone-
pyridinyl compounds and fluoro-pyrimidinyl-methoxy Substituted pyridinone-pyridi nyl …

Anti-fibrotic pyridinones

BO Buckman, JB Nicholas, JY Ramphal… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
50435378&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Substituted oxadiazolyl pyridinones and oxadiazolyl pyridazinones as hif inhibitors

M Härter, H Beck, P Ellinghaus… - US Patent App. 14 …, 2014 - Google Patents
The present application relates to novel substituted 5-(1, 2, 4-oxadiazol-5-yl) pyridin-2-ones
and 6-(1, 2, 4-oxadiazol-5-yl) pyridazin-3-ones, to processes for their preparation, to their …