Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …

Reverse engineering the brain by mimicking the structure and function of neuronal networks
on a silicon integrated circuit was the original goal of neuromorphic engineering, but …

Current electrophysiological or optical techniques cannot reliably perform simultaneous
intracellular recordings from more than a few tens of neurons. Here we report a …

Chronic imaging of neuronal networks in vitro has provided fundamental insights into
mechanisms underlying neuronal function. Current labeling and optical imaging methods …

Comparing neuronal microcircuits across different brain regions, species and individuals
can reveal common and divergent principles of network computation. Simultaneous patch …

The development of microelectrode arrays (MEAs) along with complementary advances in
electronics, mechanics and software to connect with these arrays has led to the in vitro …

The synchronous activity of neuronal networks is considered crucial for brain function.
However, the interaction between single-neuron activity and network-wide activity remains …

The patch-clamp technique is one of the best approaches to investigate neural excitability.
Impressive improvements towards the automation of the patch-clamp technique have been …

Axons convey information in neuronal circuits via reliable conduction of action potentials
(APs) from the axon initial segment (AIS) to the presynaptic terminals. Recent experimental …

In vitro neuronal models have become an important tool to study healthy and diseased
neuronal circuits. The growing interest of neuroscientists to explore the dynamics of …