[HTML][HTML] Overcoming the cellular barriers and beyond: Recent progress on cell penetrating peptide modified nanomedicine in combating physiological and …

Y Liu, Z Zhao, M Li - Asian Journal of Pharmaceutical Sciences, 2022 - Elsevier
The complex physiological and pathological conditions form barriers against efficient drug
delivery. Cell penetrating peptides (CPPs), a class of short peptides which translocate drugs …

Biomedical applications of peptide-gold nanoarchitectonics

S Maghsoudian, E Sajjadi, N Hadavi, M Soltani… - International Journal of …, 2024 - Elsevier
Gold nanoparticles (AuNPs) have become a focus of interest in biomedicine due to their
unique properties. By attaching peptides to these nanoparticles (NPs), they can be utilized …

COVID-19 diagnosis by SARS-CoV-2 Spike protein detection in saliva using an ultrasensitive magneto-assay based on disposable electrochemical sensor

ED Nascimento, WT Fonseca, TR de Oliveira… - Sensors and Actuators B …, 2022 - Elsevier
The outbreak of the COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome of
Coronavirus 2 (SARS-CoV-2), has fueled the search for diagnostic tests aiming at the control …

[HTML][HTML] Immobilization of l-asparaginase on gold nanoparticles for novel drug delivery approach as anti-cancer agent against human breast carcinoma cells

AG Al-Dulimi, AZ Al-Saffar, GM Sulaiman… - Journal of Materials …, 2020 - Elsevier
Abstract l-asparaginase is an amidohydrolase enzyme that is widely identified as one of the
most potential anti cancerous drugs. Nevertheless, this drug is poorly bioavailable and …

Supramolecular peptide nanofiber/PLGA nanocomposites for enhancing pulmonary drug delivery

U Chintapula, S Yang, T Nguyen, Y Li… - … Applied Materials & …, 2022 - ACS Publications
Effective drug delivery to pulmonary sites will benefit from the design and synthesis of novel
drug delivery systems that can overcome various tissue and cellular barriers. Cell …

Inhibition of tumor metastasis by targeted daunorubicin and dioscin codelivery liposomes modified with PFV for the treatment of non-small-cell lung cancer

Y Wang, M Fu, J Liu, Y Yang, Y Yu, J Li… - International journal …, 2019 - Taylor & Francis
Background: Chemotherapy for non-small-cell lung cancer (NSCLC) still leads to
unsatisfactory clinical prognosis because of poor active targeting and tumor metastasis …

Approaches for evaluation of novel CPP-based cargo delivery systems

L Porosk, Ü Langel - Frontiers in Pharmacology, 2022 - frontiersin.org
Cell penetrating peptides (CPPs) can be broadly defined as relatively short synthetic, protein
derived or chimeric peptides. Their most remarkable property is their ability to cross cell …

Anchor, spacer, and ligand-modified engineered exosomes for trackable targeted therapy

C Kang, P Han, JS Lee, D Lee, D Kim - Bioconjugate Chemistry, 2020 - ACS Publications
Exosomes have been widely demonstrated as an effective anticancer therapeutic moiety.
However, their clinical translation has been limited by the requirement of prohibitively high …

Potential anticancer activity of a new pro-apoptotic peptide–thioctic acid gold nanoparticle platform

M Akrami, S Samimi, M Alipour, H Bardania… - …, 2021 - iopscience.iop.org
Targeted nanoparticle platforms designed to induce cell death by apoptosis can bypass the
resistance mechanisms of cancer cells. With this in mind we have constructed a new cancer …

Prospect of cell penetrating peptides in stem cell tracking

X Zhang, T Lei, H Du - Stem Cell Research & Therapy, 2021 - Springer
Stem cell therapy has shown great efficacy in many diseases. However, the treatment
mechanism is still unclear, which is a big obstacle for promoting clinical research. Therefore …