Environmentally sensitive fluorescent nucleoside analogues as probes for nucleic acid–protein interactions: molecular design and biosensing applications

D Dziuba - Methods and Applications in Fluorescence, 2022 - iopscience.iop.org
Fluorescent nucleoside analogues (FNAs) are indispensable in studying the interactions of
nucleic acids with nucleic acid-binding proteins. By replacing one of the poorly emissive …

Secondary structure across the bacterial transcriptome reveals versatile roles in mRNA regulation and function

C Del Campo, A Bartholomäus, I Fedyunin… - PLoS …, 2015 - journals.plos.org
Messenger RNA acts as an informational molecule between DNA and translating
ribosomes. Emerging evidence places mRNA in central cellular processes beyond its major …

Reversible regulation of enzyme activity by pH-responsive encapsulation in DNA nanocages

SH Kim, KR Kim, DR Ahn, JE Lee, EG Yang, SY Kim - ACS nano, 2017 - ACS Publications
Reversible regulation of enzyme activity by chemical and physical stimuli is often achieved
by incorporating stimuli-responsive domains in the enzyme of interest. However, this method …

Redox-responsive polymeric nanocomplex for delivery of cytotoxic protein and chemotherapeutics

WQ Lim, SZF Phua, Y Zhao - ACS applied materials & interfaces, 2019 - ACS Publications
Responsive delivery of anticancer proteins into cells is an emerging field in biological
therapeutics. Currently, the delivery of proteins is highly compromised by multiple …

Homogeneous electrochemiluminescence biosensor for the detection of RNase A activity and its inhibitor

J Ni, H Lin, W Yang, Y Liao, Q Wang, F Luo… - Analytical …, 2019 - ACS Publications
Ribonuclease A (RNase A) is increasingly considered as a biomarker for tumor diagnosis,
and it is of great significance to develop an ultrasensitive, cost-effective assay for RNase A …

Yeast-and antibody-based tools for studying tryptophan C-mannosylation

A John, MA Järvå, S Shah, R Mao, S Chappaz… - Nature Chemical …, 2021 - nature.com
Tryptophan C-mannosylation is an unusual co-translational protein modification performed
by metazoans and apicomplexan protists. The prevalence and biological functions of this …

Sensitive detection of RNase a activity and collaborative drug screening based on rGO and fluorescence probe

C Tong, C Zhao, B Liu, B Li, Z Ai, J Fan… - Analytical …, 2018 - ACS Publications
In addition to being an important object in theoretical and experimental studies in
enzymology, RNase A also plays an important role in the development of many kinds of …

A catalytic protein–proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S

Z Hegedus, CM Grison, JA Miles… - Chemical …, 2019 - pubs.rsc.org
Foldamers are abiotic molecules that mimic the ability of bio-macromolecules to adopt well-
defined and organised secondary, tertiary or quaternary structure. Such templates have …

An unintentional discovery of a fluorogenic DNA probe for ribonuclease I

D Chang, T Chang, B Salena, Y Li - ChemBioChem, 2020 - Wiley Online Library
Ribonuclease I belongs to a class of nonspecific endoribonucleases and plays many
important roles in a variety of biological and cellular processes. While their ubiquitous nature …

The p30 protein of the African swine fever virus behaves as an RNase

S Nandy, NR Bora, S Gaurav, S Kumar - Virology, 2024 - Elsevier
Abstract The African Swine Fever Virus (ASFV) is responsible for causing African Swine
Fever (ASF), a severe contagious disease characterized by hemorrhagic symptoms. The …