Dopamine receptor signaling
KA Neve, JK Seamans… - Journal of receptors and …, 2004 - Taylor & Francis
The D1-like (D1, D5) and D2-like (D2, D3, D4) classes of dopamine receptors each has
shared signaling properties that contribute to the definition of the receptor class, although …
shared signaling properties that contribute to the definition of the receptor class, although …
Role of dopamine receptors in ADHD: a systematic meta-analysis
J Wu, H Xiao, H Sun, L Zou, LQ Zhu - Molecular neurobiology, 2012 - Springer
The dopaminergic system plays a pivotal role in the central nervous system via its five
diverse receptors (D1–D5). Dysfunction of dopaminergic system is implicated in many …
diverse receptors (D1–D5). Dysfunction of dopaminergic system is implicated in many …
Microbes & neurodevelopment–Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala
The mammalian amygdala is a key emotional brain region for eliciting social behaviour,
critically involved in anxiety and fear-related behaviours, and hence a focus of research on …
critically involved in anxiety and fear-related behaviours, and hence a focus of research on …
Biased signaling of G protein coupled receptors (GPCRs): Molecular determinants of GPCR/transducer selectivity and therapeutic potential
M Seyedabadi, MH Ghahremani, PR Albert - Pharmacology & therapeutics, 2019 - Elsevier
G protein coupled receptors (GPCRs) convey signals across membranes via interaction with
G proteins. Originally, an individual GPCR was thought to signal through one G protein …
G proteins. Originally, an individual GPCR was thought to signal through one G protein …
The dopamine D4 receptor: one decade of research
JN Oak, J Oldenhof, HHM Van Tol - European journal of pharmacology, 2000 - Elsevier
Dopamine is an important neurotransmitter involved in motor control, endocrine function,
reward, cognition and emotion. Dopamine receptors belong to the superfamily of G protein …
reward, cognition and emotion. Dopamine receptors belong to the superfamily of G protein …
[HTML][HTML] Oligomerization of μ-and δ-opioid receptors: generation of novel functional properties
SR George, T Fan, Z Xie, R Tse, V Tam… - Journal of Biological …, 2000 - ASBMB
The existence of dimers and oligomers for many G protein-coupled receptors has been
described by us and others. Since many G protein-coupled receptor subtypes are highly …
described by us and others. Since many G protein-coupled receptor subtypes are highly …
[HTML][HTML] Gi/o Protein-Dependent and -Independent Actions of Pertussis Toxin (PTX)
S Mangmool, H Kurose - Toxins, 2011 - mdpi.com
Pertussis toxin (PTX) is a typical AB toxin. The A-protomer (S1 subunit) exhibits ADP-
ribosyltransferase activity. The B-oligomer consists of four subunits (S2 to S5) and binds …
ribosyltransferase activity. The B-oligomer consists of four subunits (S2 to S5) and binds …
Ion channels and signaling in the pituitary gland
Endocrine pituitary cells are neuronlike; they express numerous voltage-gated sodium,
calcium, potassium, and chloride channels and fire action potentials spontaneously …
calcium, potassium, and chloride channels and fire action potentials spontaneously …
Acute administration of dopaminergic drugs has differential effects on locomotion in larval zebrafish
TD Irons, PE Kelly, DL Hunter, RC Macphail… - Pharmacology …, 2013 - Elsevier
Altered dopaminergic signaling causes behavioral changes in mammals. In general,
dopaminergic receptor agonists increase locomotor activity, while antagonists decrease …
dopaminergic receptor agonists increase locomotor activity, while antagonists decrease …
The dopamine D4 receptor gene 48-base-pair-repeat polymorphism and mood disorders: a meta-analysis
BACKGROUND: We conducted a meta-analysis to re-evaluate the role of the dopamine D4
receptor gene 48-base-pair-repeat (DRD4) polymorphism in mood disorders. METHODS …
receptor gene 48-base-pair-repeat (DRD4) polymorphism in mood disorders. METHODS …