The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is
primarily conformed of glycoproteins and proteoglycans, which provide communication …

Obesity and aging have both seen dramatic increases in prevalence throughout society.
This review seeks to highlight common pathologies that present with obesity, along with the …

Over the past couple of decades, accumulating evidence has shown that structural and
functional abnormalities of coronary microvasculature are highly prevalent, associated with …

Hypertension is a primary risk factor for cardiovascular disease. Cardiovascular disease is
the leading cause of death among adults worldwide. In this review, we focus on two of the …

Despite decades of efforts to reduce sodium intake, excess dietary sodium remains
commonplace, and contributes to increased cardiovascular morbidity and mortality …

Cardiovascular (CV) stiffening represents a complex series of events evolving from
pathological changes in individual cells of the vasculature and heart which leads to overt …

The vascular endothelium is a multifunctional cellular system which directly influences blood
components and cells within the vessel wall in a given tissue. Importantly, this cellular …

The coronary microvasculature plays a key role in regulating the tight coupling between
myocardial perfusion and myocardial oxygen demand across a wide range of cardiac …

Obesity has a strong impact on the pathogenesis of cardiovascular disease, which raises
enthusiasm to understand how excess adiposity causes vascular injury. Adipose tissue is an …

The endothelial glycocalyx is an extracellular matrix that coats the endothelium and extends
into the lumen of blood vessels, acting as a barrier between the vascular wall and blood …