Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex
pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which …

Monogenic diabetes includes several clinical conditions generally characterized by early-
onset diabetes, such as neonatal diabetes, maturity-onset diabetes of the young (MODY) …

Clinical laboratory tests are a critical component of the continuum of care. We evaluate the
genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n …

Monogenic diabetes results from one or more defects in a single gene. The disease may be
inherited within families as a dominant, recessive or non-Mendelian trait or may present as a …

Maturity-onset diabetes of the young (MODY) is characterized by autosomal dominant
inheritance, onset before 25 years of age, absence of β-cell autoimmunity, and sustained …

ISPAD Clinical Practice Consensus Guidelines 2022: The diagnosis and management of
monogenic diabetes in children and adolescents - PMC Back to Top Skip to main content NIH …

The precision medicine approach of tailoring treatment to the individual characteristics of
each patient or subgroup has been a great success in monogenic diabetes subtypes, MODY …

Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a recently defined entity
that includes rare kidney diseases characterized by tubular damage and interstitial fibrosis …

Soluble sugars serve five main purposes in multicellular organisms: as sources of carbon
skeletons, osmolytes, signals, and transient energy storage and as transport molecules …

Congenital anomalies of the kidney and urinary tract (CAKUT) refer to a spectrum of
structural renal malformations and are the leading cause of end-stage renal disease in …