Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine

FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …

Mesenchymal stem cell secretome as an emerging cell-free alternative for improving wound repair

P Ahangar, SJ Mills, AJ Cowin - International journal of molecular …, 2020 - mdpi.com
The use of mesenchymal stem cells (MSC) for the treatment of cutaneous wounds is
currently of enormous interest. However, the broad translation of cell therapies into clinical …

Current status of the applications of conditioned media derived from mesenchymal stem cells for regenerative medicine

V Smolinska, M Boháč… - Physiological research, 2023 - pmc.ncbi.nlm.nih.gov
Recently published studies suggest that the paracrine substances released by
mesenchymal stem cells (MSCs) are the primary motive behind the therapeutic action …

An In Vitro and In Vivo Comparison of Osteogenic Differentiation of Human Mesenchymal Stromal/Stem Cells

J Mollentze, C Durandt, MS Pepper - Stem cells international, 2021 - Wiley Online Library
The use of stem cells in regenerative medicine, including tissue engineering and
transplantation, has generated a great deal of enthusiasm. Mesenchymal stromal/stem cells …

Stem cell-based therapy: a promising treatment for diabetic foot ulcer

R El Hage, U Knippschild, T Arnold, I Hinterseher - Biomedicines, 2022 - mdpi.com
Diabetic foot ulcer (DFU) is a severe complication of diabetes and a challenging medical
condition. Conventional treatments for DFU have not been effective enough to reduce the …

Musculoskeletal tissue engineering with human umbilical cord mesenchymal stromal cells

L Wang, L Ott, K Seshareddy, ML Weiss… - Regenerative …, 2011 - Taylor & Francis
Multipotent mesenchymal stromal cells (MSCs) hold tremendous promise for tissue
engineering and regenerative medicine, yet with so many sources of MSCs, what are the …

Different donors mesenchymal stromal cells secretomes reveal heterogeneous profile of relevance for therapeutic use

A Assoni, G Coatti, MC Valadares… - Stem cells and …, 2017 - liebertpub.com
Duchenne muscular dystrophy (DMD) is a lethal X-linked disorder caused by null mutations
in the dystrophin gene. Although the primary defect is the deficiency of muscle dystrophin …

Mesenchymal stromal cell‐derived extracellular vesicles as cell‐free biologics for the ex vivo expansion of hematopoietic stem cells

P Budgude, V Kale, A Vaidya - Cell biology international, 2020 - Wiley Online Library
Hematopoietic stem cell transplantation (HSCT) is the ultimate choice of treatment for
patients with hematological diseases and cancer. The success of HSCT is critically …

Myogenic cell transplantation in genetic and acquired diseases of skeletal muscle

O Boyer, G Butler-Browne, H Chinoy, G Cossu… - Frontiers in …, 2021 - frontiersin.org
This article will review myogenic cell transplantation for congenital and acquired diseases of
skeletal muscle. There are already a number of excellent reviews on this topic, but they are …

Human endometrial-derived mesenchymal stem cells suppress inflammation in the central nervous system of EAE mice

JPS Peron, T Jazedje, WN Brandao, PM Perin… - Stem Cell Reviews and …, 2012 - Springer
Mesenchymal stromal cells (MSCs) are undifferentiated multipotent cells endowed with the
capacity for self-renewal and the potential to differentiate into several distinct cell lineages …