In drug development, there are typically a series of preclinical studies that must be
completed with new compounds or regimens before use in humans. A sequence of in vitro …

The aim of this study was to identify a candidate drug for the development of anti-
tuberculosis therapy from previously synthesized compounds based on the …

Tuberculosis (TB) remains among the world's great public health challenges. Worldwide
resurgence of TB is due to two major problems: the AIDS epidemic, which started in the mid …

Background Tuberculosis (TB) is a global burden with one–third of the world's population
infected with the pathogen Mycobacterium tuberculosis complex and annually 1.4 million …

Objectives Tuberculosis drug development is hampered by the slow growth of
Mycobacterium tuberculosis. Bioluminescence, light produced by an enzymatic reaction …

Background: Chitosan nanoparticles have gained growing interest for nanomedicine,
biomedical engineering and development of new therapeutic with improved bioavailability …

We and others recently identified copper resistance as important for virulence of
Mycobacterium tuberculosis. Here, we introduce a high-throughput screening assay for …

ABSTRACT In Mexican Traditional Medicine 187 plant species are used in the treatment of
respiratory conditions that may be associated with tuberculosis. In this contribution, we …

The synthesis, characterization and the anti-Mycobacterium tuberculosis (MTB) activities of
three ruthenium complexes containing the 2-pyridinecarboxylic acid anion (picolinate), with …

Background The ethnic population of Arunachal Pradesh uses a number of orchids as such,
or in decoction for various ailments. Three untapped orchids namely, Rhynchostylis retusa …