The convenient and sensitive detection of metabolites is of great significance for
understanding human health status and drug development. Solid-phase …

Objectives: Dabrafenib is used as an active pharmaceutical ingredient acts as an inhibitor of
the associated enzyme B-Raf, which plays a role in the regulation of cell growth. In the …

Drug metabolism is very important in determining the safety and efficacy of the drug. We
worked towards this direction and designed a new strategy to study the in vitro metabolites …

A rapid, simple and highly sensitive stability-indicating reverse-phase high-performance
liquid chromatographic technique, coupled with a photodiode array detector, was developed …

Objectives: Forced degradation study of the drug product and drug substance is very much
important in drug development and drug discovery to establish the intrinsic stability and …

Teneligliptin (TEN) is a novel, third-generation DPP4 inhibitor (Dipeptidyl peptidase) used
for the treatment of Type 2 Diabetes Mellitus. A rapid, simple and highly sensitive stability …

A simple, rapid, sensitive, and cost-effective green solvent-assisted reverse-phase high-
performance liquid chromatographic technique, coupled with a photodiode array detector …

Abstract According to Food and Drug Administration requirements, a simple, sensitive and
specific liquid chromatography-tandem mass spectrophotometry method for quantifying …