Alzheimer's disease (AD) is characterized pathologically by the deposition of β-amyloid
peptides (Aβ) and the accumulation of neurofibrillary tangles (NFTs) composed of hyper …

The prevalence of hearing problems in the Western world has, due to aging of the
population, doubled over the past 30 years. Thereby, noise-induced hearing loss is an …

Alterations in inhibitory interneurons contribute to cognitive deficits associated with several
psychiatric and neurological diseases. Phasic and tonic inhibition imparted by γ …

Schizophrenia is a brain disorder associated with cognitive deficits that severely affect the
patients′ capacity for daily functioning. Whereas our understanding of its pathophysiology …

Abstract System xc− represents an intriguing target in attempts to understand the
pathological states of the central nervous system. Also called a cystine-glutamate antiporter …

This article describes commonly used experimental and clinical biomarkers of neuronal
injury and neurodegeneration for the evaluation of neuropathology and monitoring of …

Working memory functions supported by the prefrontal cortex decline in normal aging.
Disruption of corticolimbic GABAergic inhibitory circuits can impair working memory in young …

Non‐Technical Summary In multiple brain regions, endogenous cannabinoids suppress
inhibitory synaptic transmission; however, the biochemical/molecular pathways for …

Cognitive effort leads to a seeming cacophony of brain oscillations. For example, during
tasks engaging working memory (WM), specific oscillatory frequency bands modulate in …

NG2 cells, oligodendrocyte precursors, play a critical role in myelination during postnatal
brain maturation, but a pool of these precursors is maintained in the adult and recruited to …