Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that
involve G-quartets linked by loop nucleotides. The structural and topological diversity of G …

The chemical composition of cells at the molecular level determines their growth,
differentiation, structure, and function. Probing this composition is powerful because it …

The control of viral outbreaks requires nucleic acid diagnostic tests that are sensitive, simple
and fast. Here, we report a highly sensitive and specific one-pot assay for the fluorescence …

Aptamers are exciting smart molecular probes for specific recognition of disease biomarkers.
A number of strategies have been developed to convert target–aptamer binding into …

The structural flexibility and small size of aptamers enable precise recognition of cellular
elements for imaging and therapeutic applications. The process by which aptamers are …

Photoacoustic-fluorescence imaging is an emerging medical imaging technology developed
in recent years that has shown immense application potential for specialties that depend on …

The cellular functions of RNA are not limited to their role as blueprints for protein synthesis.
In particular, noncoding RNA, such as, snRNAs, lncRNAs, miRNAs, play important roles …

Guanine (G)-quadruplexes (G4s) are unique nucleic acid structures that are formed by
stacked G-tetrads in G-rich DNA or RNA sequences. G4s have been reported to play …

An RNA-based fluorogenic module consists of a light-up RNA aptamer able to specifically
interact with a fluorogen to form a fluorescent complex. Over the past decade, significant …

Functional nucleic acids with fluorescence properties are powerful research tools for both
biomolecular analysis and biological nanomaterials. This review collected these interesting …